Evidence map›Paper›PMID 40188290›Full record

SynthesisBritish journal of cancer2025

De novo colorectal cancer after kidney transplantation: a systematic review and meta-analysis.

Bima J Hasjim, Arsha Ostowari, Monique Gandawidjaja, Mohsen D Mohammadi, Linda Suk-Ling Murphy, Matthew D Whealon, Valery Vilchez, Hirohito Ichii, Robert R Redfield, Oliver S Eng

Abstract readSystematic ReviewMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in British journal of cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Bima J HasjimDepartment of Surgery, University of California, Orange, CA, USA.
Arsha OstowariDepartment of Surgery, University of California, Orange, CA, USA.
Monique GandawidjajaDepartment of Surgery, University of California, Orange, CA, USA.
Mohsen D MohammadiIndustrial Engineering and Management Sciences, Northwestern University, Evanston, IL, USA.
Linda Suk-Ling MurphyResearch Librarian for Health Sciences, University of California, Irvine, CA, USA.
Matthew D WhealonDivision of Colon and Rectal Surgery, Department of Surgery, University of California, Orange, CA, USA.
Valery VilchezDivision of Colon and Rectal Surgery, Department of Surgery, University of California, Orange, CA, USA.
Hirohito IchiiDivision of Transplantation, Department of Surgery, University of California Irvine School of Medicine, Orange, CA, USA.
Robert R RedfieldDivision of Transplantation, Department of Surgery, University of California Irvine School of Medicine, Orange, CA, USA.
Oliver S EngDivision of Surgical Oncology, Department of Surgery, University of California, Orange, CA, USA. oeng@hs.uci.edu.ORCID http://orcid.org/0000-0003-0226-5005

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundKidney transplant (KT) patients have higher risks of developing de novo colorectal cancer (CRC) compared to the general population. However, there is still a knowledge gap in their clinical characteristics, as most single- or multi-center efforts are underpowered and lack generalizability.

methodsPubMed, Web of Science, Cochrane CENTRAL, and Scopus databases were queried for studies published until July 22

resultsThere were 49 articles included involving 1855 KT patients who developed CRC. The mean time from transplantation to CRC diagnosis was 8·7 years (95%CI 7·2, 10·3 years; I

conclusionsDe novo CRC was diagnosed in under 10 years after KT, and nearly 40% of patients already have advanced stage disease at diagnosis. The pooled rate of 5-year survival was 31.8%. However, there was wide heterogeneity between studies and further research is required. PROSPERO Registration: CRD42023415767.

Indexed as

Colorectal NeoplasmsKidney TransplantationHumansRisk Factors

Identifiers

PMID40188290
PMCPMC12119885

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.