Trial reportJournal of perinatology : official journal of the California Perinatal Association2025
Initiation of enteral feeding as per current protocol (at 24 h) versus as per clinical status (from 6 h onwards) in neonates born with antenatal reversed end diastolic flow (REDF) in the umbilical artery Doppler: a pilot randomized controlled trial.
Trial report in Journal of perinatology : official journal of the California Perinatal Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Safety and Tolerability of Early Minimal Enteral Nutrition from Birth in Preterm Neonates with Antenatal Doppler Abnormalities.Indian journal of pediatrics · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo compare the effects of initiating feeds at 24 h versus at 6 h in neonates with reversed end-diastolic flow (REDF) and determine the incidence of feed intolerance (FI) and necrotizing enterocolitis (NEC).
designPilot randomized controlled trial.
methodsNeonates with REDF (n = 52) were randomized to start feeds at 6 h (n = 26) or 24 h (n = 26) to assess FI, NEC, time to full feeds, sepsis, mortality, weight and gestation at discharge, and hospital stay.
resultsFI was observed in 14 (54%) neonates in 6 h group and 17 (65%) in 24 h group, with comparable NEC rates. Neonates in the 6 h group achieved full feeds faster (8 vs. 11 days) and had shorter hospital stay (17 vs. 32 days). Death and sepsis rates were similar.
conclusionsFeed initiation at 6 h in REDF neonates did not increase the risk of FI or NEC.
trial registrationClinical trial registry of India (CTRI/2023/02/050025); 23/02/2023.
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Identifiers
40188272What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.