Evidence map›Paper›PMID 40188212›Full record

ArticleScientific reports2025

Development and deployment of a functional 3D-bioprinted blood vessel.

Annika C Dell, Jamie Maresca, Bruce A Davis, Toshihiko Isaji, Alan Dardik, John P Geibel

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Review
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  5. Article
  6. Review
  7. Review
  8. Article
  9. A bioprinted model of pregnant human uterine myometrium.Frontiers in bioengineering and biotechnology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Annika C DellThe John B. Pierce Laboratory, Inc, New Haven, CT, 06519, USA. annika.dell@imte.fraunhofer.de.
Jamie MarescaThe John B. Pierce Laboratory, Inc, New Haven, CT, 06519, USA.
Bruce A DavisThe John B. Pierce Laboratory, Inc, New Haven, CT, 06519, USA.
Toshihiko IsajiDivision of Vascular Surgery, Department of Surgery, Yale School of Medicine, New Haven, Connecticut, CT, 06510, USA.
Alan DardikDepartment of Cellular and Molecular Physiology, Yale School of Medicine, New Haven, Connecticut, CT, 06510, USA.
John P GeibelThe John B. Pierce Laboratory, Inc, New Haven, CT, 06519, USA. john.geibel@yale.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Creating vascular structures in vitro via bioprinting to replace damaged or missing vasculature has significant advantages over current surgical methods of vessel replacement. Using rat fibroblasts and smooth muscle cells, we have bioprinted a rat aorta using a rotating mandrel method to create the tubular replacement structure. Then, the 3D-bioprinted aortas were implanted into rats to determine their functionality long-term in vivo. The implanted vascular conduits were well-tolerated, well-incorporated into native vasculature, and showed the physiological behavior of a native vessel. The development and deployment of 3D-bioprinted vessels for repair of large vessels in an animal model paves the way for advancements in the treatment of vascular disease in humans.

Indexed as

AortaBioprintingBlood Vessel ProsthesisPrinting, Three-DimensionalTissue EngineeringAnimalsFibroblastsMaleMyocytes, Smooth MuscleRatsTissue Scaffolds

Identifiers

PMID40188212
PMCPMC11972400

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.