SynthesisHealth and quality of life outcomes2025
Psychosocial factors associated with quality of life in cancer patients undergoing treatment: an umbrella review.
Synthesis in Health and quality of life outcomes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Use of AI to Predict and Support Medication Adherence in Patients With Breast Cancer: Systematic Review.JMIR cancer · 2026Pooled it
- Health-related quality of life assessment in trials testing tyrosine kinase inhibitors or immune checkpoints inhibitors in early-stage NSCLC.The oncologist · 2025Pooled it
- The lived experiences of social isolation among cancer patients: a systematic review and meta-synthesis.International journal of nursing studies advances · 2026Review
- Oncofertility information interventions in patients with cancer: A systematic review and meta-analysis.Asia-Pacific journal of oncology nursing · 2026Review
- Data-driven biopsychosocial profiles to inform early psycho-oncology triage in head and neck cancer : A cross-sectional cluster analysis integrating patient-reported outcomes, medical complexity, and early psychosocial care utilization in an interdisciplinary fast-track diagnostic program.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Addressing Existential Distress Through Compassion: Feasibility and Preliminary Effects of Compassion With You (COMwithU), a Compassion-Based Intervention for Patients With Cancer.Psycho-oncology · 2026Article
- Content Validation of Primary Care Network Assessment Scale for Palliative Care Patients (ARCP) and Clinical Utility in Patients With Advanced Cancer.Scandinavian journal of caring sciences · 2026Article
- Quality of Life and Symptoms of Anxiety and Depression Among Patients With Cancer: Insights From a Tertiary Care Hospital.Medical science monitor : international medical journal of experimental and clinical research · 2026Article
- Does Age Matter? A Comparison of Personality Profiles in Adult and Older Patients with Cancer Using the Structural Analysis of Social Behavior (SASB).Healthcare (Basel, Switzerland) · 2026Article
- Article
- The Interplay of Quality of Life and Satisfaction with Nursing Care in Cancer Patients: A Narrative Review.Clinics and practice · 2026Review
- Risk of employment separation among workers with head and neck cancer: a longitudinal cohort study in Turin.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Cancer pain and its impact on quality of life, distress, and spiritual well-being in the war-torn Gaza Strip.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Perceptions and Use of Clinical Practice Guidelines in Psychosocial Oncology-A Pan-Canadian Survey of Mental Health and Social Service Professionals.Current oncology (Toronto, Ont.) · 2026Article
- Social Support Across the Cancer Care Continuum in Malawi: Narratives from Cancer Survivors.SSM. Qualitative research in health · 2026Article
- Exploring health system factors related to the quality of life of people with (a history of) cancer: a rapid review.Health and quality of life outcomes · 2026Review
- Health-Related Quality of Life Changes in Patients with Digestive Cancers and Chronic Digestive Diseases: A Prospective, Multicenter Study.Journal of clinical medicine · 2026Article
- Impact of unmet needs on health-related quality of life among cancer survivors in Ulsan, Korea.BMC cancer · 2026Article
- Article
- Factors associated with serious psychological distress among US adult cancer survivors: a cross-sectional observational analysis of the 2024 National Health Interview Survey.Journal of cancer survivorship : research and practice · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
22 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCancer treatment greatly impacts physical and psychological functioning of cancer patients, negatively affecting their quality of life (QoL). This Umbrella Review (UR) aims to systematically summarize psychological and social factors positively or negatively associated with QoL in cancer patients undergoing treatment.
methodFour scientific databases (PubMed, Embase, Scopus, and PsycInfo) were searched to identify systematic reviews between 2012 and 2023 analyzing the relationship between QoL and psychosocial factors in cancer patients in treatment. The UR was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) and Joanna Briggs Institute (JBI) review guidelines. The methodological quality of the included studies was evaluated using Assessment of Multiple Systematic Reviews 2 (AMSTAR2).
resultsEighteen systematic reviews were included. The major psychological factors influencing QoL are depression, coping strategies, anxiety, and distress. Results also demonstrate the significant impact of social factors on QoL: perceived social support has a positive influence on QoL of cancer patients, while lowered social support, impaired social functioning, interactions, and role limitations worsen their QoL and overall well-being.
conclusionThis UR provides a comprehensive overview of the psychosocial factors impacting QoL of cancer patients and serves as a prominent base for developing questionnaires and policies aimed at measuring QoL in cancer patients undergoing treatment. Moreover, the findings of the study can guide future research or the development of personalized clinical interventions aimed at improving QoL for this cancer population group.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.