Evidence map›Paper›PMID 40188132›Full record

Observational studyScientific reports2025

The difference in clinical features of acute acquired concomitant esotropia between adolescents and adults: a prospective observational cohort study.

Jiayu Chen, Huijian Li, Jie Hao, Jiawen Liu, Zhaojun Meng, Meixv Wang, Yang Gao, Jing Fu

Abstract readObservational Study
In one paragraph

Observational study in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jiayu Chen *Beijing Tongren Eye Center, Beijing Tongren Hospital, Beijing Key Laboratory of Ophthalmology and Visual Sciences, Capital Medical University, No. 1, Dong Jiao Min Xiang Street, Dongcheng District, Beijing, 100730, China.
Huijian Li *Beijing Tongren Eye Center, Beijing Tongren Hospital, Beijing Key Laboratory of Ophthalmology and Visual Sciences, Capital Medical University, No. 1, Dong Jiao Min Xiang Street, Dongcheng District, Beijing, 100730, China.
Jie HaoBeijing Tongren Eye Center, Beijing Tongren Hospital, Beijing Key Laboratory of Ophthalmology and Visual Sciences, Capital Medical University, No. 1, Dong Jiao Min Xiang Street, Dongcheng District, Beijing, 100730, China.
Jiawen LiuWilmer Eye Institute, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.
Zhaojun MengBeijing Tongren Eye Center, Beijing Tongren Hospital, Beijing Key Laboratory of Ophthalmology and Visual Sciences, Capital Medical University, No. 1, Dong Jiao Min Xiang Street, Dongcheng District, Beijing, 100730, China.
Meixv WangBeijing Tongren Eye Center, Beijing Tongren Hospital, Beijing Key Laboratory of Ophthalmology and Visual Sciences, Capital Medical University, No. 1, Dong Jiao Min Xiang Street, Dongcheng District, Beijing, 100730, China.
Yang GaoBeijing Tongren Eye Center, Beijing Tongren Hospital, Beijing Key Laboratory of Ophthalmology and Visual Sciences, Capital Medical University, No. 1, Dong Jiao Min Xiang Street, Dongcheng District, Beijing, 100730, China.
Jing FuBeijing Tongren Eye Center, Beijing Tongren Hospital, Beijing Key Laboratory of Ophthalmology and Visual Sciences, Capital Medical University, No. 1, Dong Jiao Min Xiang Street, Dongcheng District, Beijing, 100730, China. fu_jing@126.com.

Funding

Beijing Municipal Administration of Hospitals QML20230205Beijing Municipal Administration of Hospitals XMLX202103Beijing Municipal Health Commission 2022-1-2053Beijing Municipal Science & Technology Commission Z201100005520044National Natural Science Foundation of China 82070998National Outstanding Youth Science Fund Project of National Natural Science Foundation of China 82101174
6 · The paper itself

Abstract

To compare the clinical features of acute acquired concomitant esotropia (AACE) between adolescents and adults. The clinical features were stratified by age and analyzed. The adolescent group included patients aged < 18 and the adult group included those aged ≥ 18. Refractive status, the angles of esotropia, angles of deviation at near and far, diplopia, and stereopsis were evaluated. p < 0.05 was considered statistically different. 59 patients were included in the adult group (31 males and 28 females; mean age 29.86 ± 9.64), and 42 patients in the adolescent group (29 males and 13 females; mean age 11.57 ± 3.98). Age was positively correlated with disease duration, fusional function, and distance stereopsis. In contrast, the age was negatively correlated with spherical equivalent-right eye (SE-Right), spherical equivalent-left eye (SE-Left), the angles of deviation at near, and the angles of deviation at distance. The refractive state of different age groups was significantly different (χ

Indexed as

EsotropiaAcute DiseaseAdolescentAdultAge FactorsChildFemaleHumansMaleProspective StudiesYoung AdultAcute acquired concomitant esotropiaDiplopiaRefraction statusStereopsis

Identifiers

PMID40188132
PMCPMC11972325

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.