Evidence map›Paper›PMID 40188076›Full record

ArticleBMC geriatrics2025

Benign skin tumors in older persons: a population-based study.

Nelli Leskelä, Laura Huilaja, Jari Jokelainen, Suvi-Päivikki Sinikumpu

Abstract read
In one paragraph

Article in BMC geriatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Menopause and skin.Menopause (New York, N.Y.) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nelli LeskeläFaculty of Medicine, University of Oulu, Oulu, Finland.
Laura HuilajaDepartment of Dermatology and Medical Research Center, Oulu University Hospital, P.B.20, Oulu, FIN-90029 OYS, Finland.
Jari JokelainenNorthern Finland Birth Cohorts, Arctic Biobank, and Infrastructure for Population Studies, Faculty of Medicine, University of Oulu, Oulu, Finland.
Suvi-Päivikki SinikumpuDepartment of Dermatology and Medical Research Center, Oulu University Hospital, P.B.20, Oulu, FIN-90029 OYS, Finland. suvi-paivikki.sinikumpu@oulu.fi.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBenign skin tumors become more common with advanced age. However, little is known about the etiology of these common lesions. Our objectives were to evaluate the risk factors for seborrheic keratosis, lentigo solaris, cherry angiomas and melanocytic nevi in an elderly population. Our candidate predisposing factors were sex, age, Fitzpatrick skin type, history of outdoor work, life style factors and anthropometric measurements and laboratory tests.

methodsIn this retrospective cross-sectional study of a large, well-documented cohort, a total body skin examination (TBSE) was performed by dermatologists. The information gathered was augmented with self-reported data. The associations between benign skin tumors and the risk factors analysed with the Chi square test, Fischer exact test and analysis of variance as appropriate.

resultsThe study included 552 participants aged between 70 and 93 years. According to the TBSE, benign skin tumors were present in up to 78.7% in certain subsets of participants. Seborrheic keratosis was the most common lesion type, and 15.6% of all cases had > 50 lesions. Seborrheic keratosis were more common in males (p < 0.05), while lentigo solaris and cherry angiomas were more common in females (p < 0.05). A history of outdoor working associated with higher number of lentigo solaris and seborrheic keratosis lesions (p < 0.05). There was an association between lower glycated haemoglobin levels and the presence of multiple cherry angiomas (p < 0.05). Female subjects with multiple cherry angiomas had higher levels of high-density cholesterol and lower triglyceride values than in those with fewer cherry angiomas (p < 0.05 for both). In males, lower mean haemoglobin levels were associated with multiple cherry angiomas (p < 0.05).

conclusionsWe found sex differences and several new possible etiological factors behind benign skin tumors which, despite being common, remain poorly characterized.

Indexed as

Population SurveillanceSkin NeoplasmsAgedAged, 80 and overCohort StudiesCross-Sectional StudiesFemaleHumansKeratosis, SeborrheicMaleRetrospective StudiesRisk FactorsBenign skin tumorCherry angiomasEtiologyLentigo solarisMelanocytic neviSeborrheic keratosisTotal body skin examination

Identifiers

PMID40188076
PMCPMC11971830

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.