Observational studyBMJ open2025
Association between emergency department to intensive care units time and in-hospital mortality: an analysis of the MIMIC-IV database.
Observational study in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- The impact of diabetes on clinical outcomes in acutely ill patients - a study on patients admitted to the emergency department.BMC cardiovascular disorders · 2026Article
- Data-Driven Phenotyping Reveals Nonuniform Association Between Age and Mortality After Aortic Surgery: Retrospective Cohort Study of UK Biobank Data.JMIR aging · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe association between the duration from the emergency department (ED) to the intensive care units (ICUs) and in-hospital mortality among patients admitted directly to the ICUs from the ED remains controversial. This study aimed to use data from the Medical Information Mart for Intensive Care-IV database to explore the relationship between the ED to ICUs time and patient outcomes.
designRetrospective observational study.
settingAdmissions to the Beth Israel Deaconess Medical Center intensive care from 2008 to 2019.
participantsA total of 15 246 adult patients were identified as admitted directly from the ED to the ICUs during their first hospitalisation. After excluding those without recorded ED registration times and those with a hospital-to-ICU admission interval exceeding 6 hours (n=2432), the final analysis cohort comprised 12 703 patients. PRIMARY AND SECONDARY OUTCOME MEASURES: The primary outcome was in-hospital all-cause mortality. Secondary outcomes included 28-day all-cause mortality and length of stay in ICU and hospital.
resultsThe median ED to ICUs time was 3.98 hours. Longer ED to ICUs times were associated with lower in-hospital mortality, decreasing from 17.6% in the shortest to 12.2% in the longest interval group, and shorter ICU stays. After propensity score weighting, adjusted logistic regression models confirmed the inverse association between longer ED to ICUs time and in-hospital mortality (OR: 0.75, 95% CI: 0.69 to 0.82, p<0.01). Restricted cubic spline analysis showed a non-linear decline in mortality risk with increasing ED to ICUs time, with a sharper reduction after 5.65 hours. Kaplan-Meier curves indicated consistently better survival in the longest interval group (p<0.01). Sensitivity analysis, reintroducing patients with hospital to ICUs times over 6 hours, confirmed the robustness of these results.
conclusionsLonger ED to ICUs time is linked to lower mortality and shorter ICU length of stay, suggesting that appropriately extending ED stays may benefit critically ill patients.
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