Evidence map›Paper›PMID 40187495›Full record

ArticleTransplantation and cellular therapy2025

A Structured Peer Support Intervention for Patients With Hematologic Malignancies Undergoing Hematopoietic Stem Cell Transplantation: Peer Support Interventionists' Perspectives.

Michelle Guo, Emma P Keane, Michael Baliousis, Lisa M Gudenkauf, Manfred N Mate-Kole, Annabella C Boardman, Isabella S Larizza, M Tim Song, Emma D Wolfe, Daniel A Schaefer and 5 more

Abstract read
In one paragraph

Article in Transplantation and cellular therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Michelle GuoDepartment of Psychiatry, Brigham and Women's Hospital, Boston, Massachusetts; Harvard Medical School, Boston, Massachusetts.
Emma P KeaneDepartment of Psychiatry, Brigham and Women's Hospital, Boston, Massachusetts.
Michael BaliousisDepartment of Clinical Psychology, Nottingham University Hospitals NHS Trust, Nottingham, United Kingdom.
Lisa M GudenkaufDepartment of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, Florida.
Manfred N Mate-KoleHarvard T.H. Chan School of Public Health, Boston, Massachusetts.
Annabella C BoardmanDepartment of Psychiatry, Brigham and Women's Hospital, Boston, Massachusetts.
Isabella S LarizzaDepartment of Psychiatry, Brigham and Women's Hospital, Boston, Massachusetts.
M Tim SongDepartment of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts.
Emma D WolfeDepartment of Health Services, University of Washington School of Public Health, Seattle, Washington State.
Daniel A SchaeferDepartment of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts.
Corey CutlerHarvard Medical School, Boston, Massachusetts; Division of Transplantation and Cellular Therapy, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.
Heather S JimDepartment of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, Florida.
Stephanie J LeeClinical Research Division, Fred Hutchinson Cancer Center and Division of Hematology-Oncology, University of Washington, Seattle, Washington State.
Areej El-JawahriHarvard Medical School, Boston, Massachusetts; Mass General Cancer Center, Massachusetts General Hospital, Boston, Massachusetts.
Hermioni L AmonooDepartment of Psychiatry, Brigham and Women's Hospital, Boston, Massachusetts; Harvard Medical School, Boston, Massachusetts; Department of Supportive Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts. Electronic address: hermioni_amonoo@dfci.harvard.edu.

Funding

A Positive Psychology Intervention for Allogeneic Stem Cell Transplant Patients.K08CA251654 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI AMONOO, HERMIONI L. · 2020 to 2024
$1.3M
NCI NIH HHS K08 CA251654
6 · The paper itself

Abstract

backgroundPeer support is emerging as an important component of supportive care for patients with hematologic malignancies, but it has not been robustly implemented in patients undergoing hematopoietic stem cell transplantation (HSCT).

objectivesThis qualitative study aimed to explore the experiences of peer support interventionists (participants) delivering a structured, 5-session, phone-delivered peer support intervention, the Supporting Transplant Experiences with Peer Program (STEPP) for patients undergoing HSCT.

methodsAdult patients who underwent allogeneic or autologous HSCT for the treatment of a hematologic malignancy within the past 3 years were eligible to volunteer in this study as trained STEPP interventionists. Semi-structured qualitative interviews were conducted to explore participants' experiences, including their motivations for volunteering, reflections on intervention delivery and on the impact of peer support, and challenges faced while serving in this role. Interviews were deductively analyzed by 2 coders using framework-guided rapid analysis.

resultsTwenty STEPP interventionists participated in this study. Participants were 65% men, with a median age of 63.5 years. Most (75%) had undergone allogeneic HSCT. Emerging themes from the qualitative interviews highlighted that participants were motivated to serve as interventionists by a sense of gratitude for their transplant care and a desire to share their transplant experiences with others. The impact of the STEPP intervention on interventionists included opportunities to process their transplant journey while also providing support to their peers. Interventionists reported a preference for free-flowing conversations, which were still guided by the structured manual. Challenges included terminating the interventionist-patient relationship at the conclusion of STEPP.

conclusionPeer support interventions for patients undergoing HSCT have the potential to enhance well-being and provide meaning for both patients preparing to undergo HSCT and HSCT survivors who serve as interventionists. Large-scale randomized clinical trials are needed to test the efficacy of peer support interventions for improving health-related outcomes among patients undergoing HSCT and HSCT survivors serving as interventionists for these interventions.

Indexed as

Hematologic NeoplasmsHematopoietic Stem Cell TransplantationPeer GroupSocial SupportAdultAgedFemaleHumansMaleMiddle AgedQualitative ResearchCancerHematologic malignancyHematopoietic stem cell transplantationPeer mentorPeer supportQuality of lifeRecoverySocial supportStem cell transplantation

Identifiers

PMID40187495
PMCPMC12146048

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.