Evidence map›Paper›PMID 40187479›Full record

ArticleToxicology2025

Regulation of in vitro human hematopoietic differentiation by dioxin-like compounds.

D M Isha Olive Khan, Robert B Crawford, Norbert E Kaminski

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxicology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

D M Isha Olive KhanInstitute for Integrative Toxicology, Michigan State University, MI, USA. Electronic address: khand@msu.edu.
Robert B CrawfordInstitute for Integrative Toxicology, Michigan State University, MI, USA.
Norbert E KaminskiInstitute for Integrative Toxicology, Michigan State University, MI, USA; Center for Research on Ingredient Safety, Michigan State University, MI, USA; Department of Pharmacology and Toxicology, Michigan State University, MI, USA. Electronic address: kamins11@msu.edu.

Funding

VOLATILE ORGANIC CONTAMINANTS--QUANTIFYING THEIR MOVEMENT IN THE UNSATURATED ZONEP42ES004911 · NIEHS · MICHIGAN STATE UNIVERSITY · PI Jamie J Bernard · 1989 to 2026
$64.9M
NIEHS NIH HHS P42 ES004911
6 · The paper itself

Abstract

Certain dioxin-like compounds (DLCs) pose health concerns. However, their impact on human hematopoiesis has not been explored. Role of 2,3,4,7,8-pentachlorodibenzofuran (PeCDF), 3,4,4',5-tetrachlorobiphenyl (PCB81), and 3,3',4,4',5-pentachlorobiphenyl (PCB126) in lineage specification from human cord-blood derived CD34

Indexed as

BenzofuransCell DifferentiationDioxinsEnvironmental PollutantsHematopoiesisHematopoietic Stem CellsPolychlorinated BiphenylsAntigens, CD34Cells, CulturedDose-Response Relationship, DrugFetal BloodHumansPolychlorinated DibenzodioxinsReceptors, Aryl Hydrocarbon2,3',4,4',5-pentachlorobiphenyl2,3,4,7,8-pentachlorodibenzofuran3,4,5,3',4'-pentachlorobiphenylAntigens, CD34BenzofuransDioxinsEnvironmental PollutantsPolychlorinated BiphenylsPolychlorinated DibenzodioxinsReceptors, Aryl HydrocarbonAryl hydrocarbon receptorDioxinsHematopoiesisImmunotoxicityIn vitroRisk assessment

Identifiers

PMID40187479
PMCPMC12160933

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.