Evidence map›Paper›PMID 40187391›Full record

ArticleEnvironmental research2025

Neighborhood deprivation and iodine levels influence air pollution effects on maternal thyroid function in early pregnancy.

Xiaoran Yang, Sandrah P Eckel, Zhongzheng Niu, Roxana Khalili, Tingyu Yang, Xinci Chen, Mario Vigil, Trevor E Angell, Fred Lurmann, Patrick J Parsons and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Environmental research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Observational
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Xiaoran YangDepartment of Population and Public Health Sciences Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Sandrah P EckelDepartment of Population and Public Health Sciences Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Zhongzheng NiuDepartment of Population and Public Health Sciences Keck School of Medicine, University of Southern California, Los Angeles, CA, USA; Department of Epidemiology and Environmental Health, School of Public Health and Health Professions, University at Buffalo, Buffalo, NY, USA.
Roxana KhaliliDepartment of Population and Public Health Sciences Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Tingyu YangDepartment of Population and Public Health Sciences Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Xinci ChenDepartment of Population and Public Health Sciences Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Mario VigilDepartment of Population and Public Health Sciences Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Trevor E AngellDivision of Endocrinology and Diabetes, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Fred LurmannSonoma Technology, Inc., Petaluma, CA, USA.
Patrick J ParsonsLaboratory of Inorganic and Nuclear Chemistry, Wadsworth Center, New York State Department of Health, Albany, NY, USA; Department of Environmental Health Sciences, University at Albany, Rensselaer, NY, USA.
Christopher D PalmerLaboratory of Inorganic and Nuclear Chemistry, Wadsworth Center, New York State Department of Health, Albany, NY, USA; Department of Environmental Health Sciences, University at Albany, Rensselaer, NY, USA.
Jill JohnstonDepartment of Population and Public Health Sciences Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Shohreh F FarzanDepartment of Population and Public Health Sciences Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Rima HabreDepartment of Population and Public Health Sciences Keck School of Medicine, University of Southern California, Los Angeles, CA, USA; Spatial Sciences Institute, University of Southern California, Los Angeles, CA, USA.
Theresa M BastainDepartment of Population and Public Health Sciences Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Carrie BretonDepartment of Population and Public Health Sciences Keck School of Medicine, University of Southern California, Los Angeles, CA, USA. Electronic address: breton@usc.edu.

Funding

Wadsworth Center's Human Health and Exposure Analysis Resource (WC-HHEAR)U2CES026542 · NIEHS · WADSWORTH CENTER · PI KANNAN, KURUNTHACHALAM, KANNAN, KURUNTHACHALAM · 2015 to 2025
$15.6M
Project 3: Maternal Exposure to Environmental Hazards and Psychosocial Stressors and Postpartum Allostatic LoadP50MD015705 · NIMHD · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BRETON, CARRIE VAN DOREN · 2020 to 2024
$8.1M
Prenatal air pollution, fetal development and early childhood obesity riskR01ES027409 · NIEHS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BRETON, CARRIE VAN DOREN · 2018 to 2022
$3.3M
NIEHS NIH HHS R01 ES027409NIEHS NIH HHS U2C ES026542NIMHD NIH HHS P50 MD015705
6 · The paper itself

Abstract

Exposure to air pollution during pregnancy that disrupts thyroid function can lead to adverse health outcomes in mother and child. We evaluated the overall effect and critical exposure window of residential ambient air pollution exposures on thyroid function in the MADRES pregnancy cohort. We also investigated whether these associations varied by iodine deficiency status and neighborhood deprivation. Early pregnancy (6-20 weeks) serum thyroid stimulating hormone (TSH) and free thyroxine (FT4) were measured for 217 mothers. Daily residential ambient air pollution exposures (PM

Indexed as

Air PollutantsAir PollutionIodineMaternal ExposureThyroid GlandAdultCohort StudiesFemaleHumansParticulate MatterPregnancyResidence CharacteristicsThyrotropinThyroxineYoung AdultAir PollutantsIodineParticulate MatterThyrotropinThyroxine

Identifiers

PMID40187391
PMCPMC12124949

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.