ReviewAnalytical sciences : the international journal of the Japan Society for Analytical Chemistry2025
Biosensing approaches in body fluids using extended-gate-type organic field-effect transistor enzymatic sensors.
Review in Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Toward non-enzymatic glucose sensing based on organic electronics: organic field-effect transistors with multifunctionalized extended-gate electrodes.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2026Review
- Novel Respiratory Disease Diagnosis Tool: Development of an Au-ReSSmall science · 2026Article
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2 authors.
Funding
Abstract
Biomarkers in body fluids provide essential chemical information for examining health conditions; however, unlike conventional instrumental approaches, easy-to-use analytical methods have not yet been fully established. This review introduces extended-gate-type organic field-effect transistors (OFETs) as biosensor platforms for real-sample analysis. OFETs are electronic devices that show switching profiles when gate voltages are applied. Therefore, the gate electrode of OFET functions as a sensing unit combined with appropriate molecular recognition materials. Owing to their signal amplification properties, OFETs enable sensitive biosensing. The extended-gate surfaces are easily functionalized with enzymatic layers using chemical modification, and these surfaces provide a high discrimination ability for specific biomarkers from their analogs. This review presents the designs of the extended-gate structures (i.e., integrated and separated styles) and their enzymatic layers and includes their actual sensing performance.
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