Evidence map›Paper›PMID 40186703›Full record

ArticleJournal of thrombosis and thrombolysis2025

Evaluation of unfractionated heparin dosing using an antifactor-Xa-based protocol in non-obese vs. obese patients for acute venous thromboembolism.

Trenton Flanagan, Monica Sharma, Uyen-Thi Cao, Xuan Wang, Vivek Kataria

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of thrombosis and thrombolysis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Trenton FlanaganDepartment of Pharmacy, Baylor University Medical Center, Dallas, TX, USA. Trenton.flanagan@gmail.com.ORCID http://orcid.org/0009-0004-8743-7092
Monica SharmaDepartment of Pharmacy, Baylor University Medical Center, Dallas, TX, USA.
Uyen-Thi CaoDepartment of Hospital Medicine, Baylor University Medical Center, Dallas, TX, USA.
Xuan WangBaylor Research Institute, Baylor Scott & White Health, Dallas, TX, USA.ORCID http://orcid.org/0000-0003-2163-7062
Vivek KatariaDepartment of Pharmacy, Baylor University Medical Center, Dallas, TX, USA.ORCID http://orcid.org/0000-0003-1149-5937

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The pharmacokinetic profile of heparin may result in supratherapeutic antifactor-Xa levels using total weight-based protocols for the treatment of venous thromboembolism (VTE) in obese patients. Previous literature has been limited by choice of monitoring assay and inconsistent dosing strategies. The goal of this study was to evaluate safety and efficacy outcomes of an antifactor-Xa based UFH VTE protocol in obese vs. non-obese patients. This was a single center, retrospective study of adult patients with an acute VTE treated with our institution specific UFH VTE protocol. Patients were screened from the preceding 3 years for inclusion into the obese (BMI ≥ 30 kg/m

Indexed as

AnticoagulantsFactor Xa InhibitorsHeparinObesityVenous ThromboembolismAcute DiseaseAdultAgedFactor XaFemaleHemorrhageHumansMaleMiddle AgedRetrospective StudiesAnticoagulantsFactor XaFactor Xa InhibitorsHeparinAnticoagulationAntifactor-XaHeparinObesityVenous thromboembolism

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.