Review in GeroScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
8 authors.
Adam GoldenOrlando Veterans Affairs Healthcare System, Orlando, FL, USA.
Cynthia WilliamsSchool of Global Health Management and Informatics, University of Central Florida, Downtown Campus, DPAC 403 C, 500 W Livingston St, Orlando, FL, 32801, USA. Cynthia.williams@ucf.edu.ORCID 0000-0002-8344-7427
Hariom YadavUSF Centre for Microbiome Research, Microbiome Institute, University of South Florida, Tampa, FL, USA.
Michal M MasternakBurnett School of Biomedical Sciences, University of Central Florida College of Medicine, Orlando, FL, USA.
Corinne LabyakDepartment of Nutrition and Dietetics, Brooks College of Health, University of North Florida, Jacksonville, FL, USA.
Peter J HollandDepartment of Neuroscience, Schmidt College of Medicine, Florida Atlantic University, Boca Raton, FL, USA.
Andrea Y ArikawaDepartment of Nutrition and Dietetics, Brooks College of Health, University of North Florida, Jacksonville, FL, USA.
Shalini JainUSF Centre for Microbiome Research, Microbiome Institute, University of South Florida, Tampa, FL, USA.
Funding
Repurposing of Metormin for Older Patients with HFpEFU01AG076928 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI KITZMAN, DALANE W, YADAV, HARIOM · 2022 to 2024
$2.3M
Gut microbiota-based biomarkers of Alzheimer's disease and its modulation by a ketogenic dietR56AG064075 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI YADAV, HARIOM · 2020 to 2021
$1.2M
Microbial therapy improves gut permeability to reduce cognitive decline and Alzheimer’s diseaseRF1AG071762 · NIA · UNIVERSITY OF SOUTH FLORIDA · PI YADAV, HARIOM · 2021 to 2021
$1.1M
Microbial therapy improves gut permeability to reduce cognitive decline and Alzheimer’s diseaseR01AG071762 · NIA · UNIVERSITY OF SOUTH FLORIDA · PI YADAV, HARIOM · 2024 to 2025
$753k
The role of gut microbiota in the efficacy of ketogenic diet to ameliorate Alzheimer's diseaseR21AG072379 · NIA · UNIVERSITY OF SOUTH FLORIDA · PI YADAV, HARIOM · 2021 to 2021
$429k
Metformin and Alzheimer's disease: Underlying Mechanisms that Ameliorate ProgressionR56AG069676 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI YADAV, HARIOM · 2020 to 2020
Gut microbiota plays a significant role in nutrient extraction, metabolism, and immune function. Thus, the growing number of microbiome studies seek to link the presence and prevalence of specific bacteria, fungi, and viruses with a variety of physiological and disease outcomes. However, recruiting a diverse group of patients has been a challenge. Poor hearing and vision, lack of transportation, cognitive impairment, and a non-English primary language may interfere with patient enrollment as well as adherence to the requirements of a Microbiome study. Much of what we do know about diseases in older adults comes from studies that exclude many of these patients commonly encountered in clinical practice. The purpose of this review article is to highlight recruitment and retention strategies for engaging people who typically do not participate in microbiome studies, and it seeks to develop and explicate inclusion and exclusion criteria to promote more robust study results.
Indexed as
Clinical Trials as TopicCognitive DysfunctionGastrointestinal MicrobiomePatient SelectionAgedHumansAgingClinicalCognitionDementiaMicrobiomeTrial
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
The selection of participants for interventional microbiota trials involving cognitively impaired older adults. · full record | OpenQuestion