Evidence map›Paper›PMID 40186657›Full record

ArticleEuropean journal of applied physiology2025

The effect of cold-water mouth swilling on thermal perceptions and heat-related symptoms for people with multiple sclerosis exercising in a hot environment.

Georgia K Chaseling, Katrina Blackett, Steve Vucic, Michael Barnett, Scott L Davis, Ollie Jay, Nicole T Vargas

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of applied physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Georgia K ChaselingThermal Ergonomics Laboratory, Heat and Health Research Centre, Faculty of Medicine and Health, University of Sydney, Camperdown, Sydney, NSW, 2006, Australia.ORCID http://orcid.org/0000-0003-3603-7852
Katrina BlackettThermal Ergonomics Laboratory, Heat and Health Research Centre, Faculty of Medicine and Health, University of Sydney, Camperdown, Sydney, NSW, 2006, Australia.
Steve VucicWestmead Clinical School, University of Sydney Clinical School, Westmead, NSW, Australia.
Michael BarnettCentral Clinical School, Sydney Medical School, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia.
Scott L DavisApplied Physiology and Sport Management, Southern Methodist University, Dallas, TX, USA.
Ollie JayThermal Ergonomics Laboratory, Heat and Health Research Centre, Faculty of Medicine and Health, University of Sydney, Camperdown, Sydney, NSW, 2006, Australia. ollie.jay@sydney.edu.au.
Nicole T VargasThermal Ergonomics Laboratory, Heat and Health Research Centre, Faculty of Medicine and Health, University of Sydney, Camperdown, Sydney, NSW, 2006, Australia.

Funding

Multiple Sclerosis Australia 15-087Multiple Sclerosis Australia 17-0227
6 · The paper itself

Abstract

purposeCold-water ingestion improves exercise capacity in the heat for people with multiple sclerosis (MS). Whether cold-water ingestion also mitigates heat-related MS symptoms is unknown. Ingesting fluid is also limiting for people with MS with impaired bladder function. Therefore, we tested the hypothesis that swilling or ingesting cold-water (7°C) compared to ingesting thermoneutral water (37°C) would mitigate the onset of perceived MS heat-related symptoms and thermal sensation in heat-sensitive people with MS during exercise in the heat.

methodsOn three occasions, 13 heat-sensitive participants with MS (41 ± 12 y; 67 ± 12 kg; 1.7 ± 0.1 m; 33.3 ± 9.4 ml·kg

resultsThermal sensation was cooler in the 7

conclusionSwilling and ingesting 7°C water induces a cooler thermal sensation in heat-sensitive people with MS exercising in the heat but does not mitigate heat-related MS symptoms. The capacity to complete 60 min of exercise with cold-water ingestion and swilling were comparable.

Indexed as

ExerciseHot TemperatureMultiple SclerosisThermosensingAdultCold TemperatureFemaleHumansMaleMiddle AgedWaterWaterCooling strategiesDemyelinationHeat intoleranceHeat sensitivityPhysical activityUhthoff’s phenomenon

Identifiers

PMID40186657
PMCPMC12423123

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.