Evidence map›Paper›PMID 40186647›Full record

ReviewAbdominal radiology (New York)2025

SpaceOAR hydrogel complications in prostate cancer radiotherapy: a pictorial review.

Maximilian Pohl, Nabih Nakrour, Yashant Aswani, Soumyadeep Ghosh, Klara Pohl, Abdelrahman Elshikh, Mankan Yatin, Rory L Cochran, Michael Fuchsjaeger, Mukesh Harisinghani

Abstract readReview
PubMed Publisher
In one paragraph

Review in Abdominal radiology (New York), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Maximilian PohlMassachusetts General Hospital, Harvard Medical School, Boston, United States. mpohl1@mgh.harvard.edu.
Nabih NakrourMassachusetts General Hospital, Harvard Medical School, Boston, United States.
Yashant AswaniUniversity of Iowa Hospitals and Clinics, Iowa City, United States.
Soumyadeep GhoshMassachusetts General Hospital, Harvard Medical School, Boston, United States.
Klara PohlMedical University of Graz, Graz, Austria.
Abdelrahman ElshikhMassachusetts General Hospital, Harvard Medical School, Boston, United States.
Mankan YatinMassachusetts General Hospital, Harvard Medical School, Boston, United States.
Rory L CochranMassachusetts General Hospital, Harvard Medical School, Boston, United States.
Michael FuchsjaegerMedical University of Graz, Graz, Austria.
Mukesh HarisinghaniMassachusetts General Hospital, Harvard Medical School, Boston, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since its approval by the United States Food and Drug Administration (FDA), the rectal hydrogel spacer system SpaceOAR (SpaceOAR™ and Space-OAR Vue™, Boston Scientific Corporation, Marlborough, Massachusetts, United States) has become widely adopted in radiation therapy protocols for prostate cancer patients. The biodegradable hydrogel creates a temporary space between the prostate and rectum, thereby effectively reducing the radiation exposure to the anterior rectal wall. While the system is generally safe, potential complications can occur and should be recognized by radiologists. This pictorial review aims to familiarize radiologists with imaging features of SpaceOAR-related complications to ensure accurate diagnosis and reporting.

Indexed as

HydrogelsProstatic NeoplasmsRadiation InjuriesHumansMaleRectumHydrogelsComplicationsHydrogel spacerProstate cancerRadiotherapySpaceOAR

Identifiers

PMID40186647

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.