Evidence map›Paper›PMID 40186412›Full record

ArticleDiabetic medicine : a journal of the British Diabetic Association2025

A validation study of the Intentional Nonadherence Scale among people with type 2 diabetes in the United Kingdom.

Vivien Teo, Anna Hodgkinson, John Weinman, Mark Chamley, Kai Zhen Yap

Abstract readValidation Study
In one paragraph

Article in Diabetic medicine : a journal of the British Diabetic Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Vivien TeoInstitute of Pharmaceutical Sciences, King's College London, London, UK.ORCID https://orcid.org/0000-0003-3054-9822
Anna HodgkinsonLambeth Diabetes Intermediate Care Team, Guy's and St Thomas' NHS Foundation Trust, London, UK.ORCID https://orcid.org/0000-0001-9375-4511
John WeinmanInstitute of Pharmaceutical Sciences, King's College London, London, UK.ORCID https://orcid.org/0000-0002-6786-0166
Mark ChamleyLambeth Diabetes Intermediate Care Team, Guy's and St Thomas' NHS Foundation Trust, London, UK.ORCID https://orcid.org/0000-0002-4596-3906
Kai Zhen YapDepartment of Pharmacy, National University of Singapore, Singapore, Singapore.ORCID https://orcid.org/0000-0002-8440-0313

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo examine the psychometric properties of the Intentional Nonadherence Scale (INAS) among people with type 2 diabetes mellitus (PwT2D) in the United Kingdom.

methodsThis validation study recruited 260 PwT2D at diabetes intermediate care team clinics in London. Thirty of them participated in the test-retest reliability analysis in 2-4 weeks, while 124 were followed up in 3-6 months for the predictive validity analysis. The psychometric evaluation also comprised internal reliability, structural validity and construct validity that assessed the relationship between the INAS and other established measures, such as the Medication Adherence Report Scale-5 (MARS-5), Beliefs about Medicine Questionnaire (BMQ)-specific, Brief Illness Perception Questionnaire (BIPQ), Patient Health Questionnaire-2 (PHQ-2) and glycated haemoglobin (HbA1c).

resultsExploratory factor analysis revealed four factors, namely 'Resisting illness', 'Resisting medication', 'Testing treatment' and 'Sensitivity to medication'. All INAS factors demonstrated high internal reliability (Cronbach's alpha = 0.92-0.96). Their test-retest reliability varied between <0.001 and 0.92. Construct validity was demonstrated by its relationship with other measures, including its negative correlations with medication adherence and positive correlations with medication concerns. Significant correlations were also found with HbA1c, as well as with PwT2D's perceptions of diabetes consequences, treatment control, identity and emotional responses to diabetes. 'Testing Treatment' showed a trend towards statistical significance with adherence in 3-6 months (coefficient = -0.34, p = 0.09).

conclusionsThe INAS performed well on a number of psychometric properties in this study. It may be a helpful tool for clinicians in identifying specific drivers of intentional nonadherence among PwT2D.

Indexed as

Diabetes Mellitus, Type 2Medication AdherenceAdultAgedFemaleGlycated HemoglobinHumansHypoglycemic AgentsMaleMiddle AgedPsychometricsReproducibility of ResultsSurveys and QuestionnairesUnited KingdomGlycated HemoglobinHypoglycemic Agentsdiabetes mellitusmedication adherencepsychometricstype 2

Identifiers

PMID40186412
PMCPMC12080987

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.