Evidence map›Paper›PMID 40186331›Full record

ArticleThe British journal of clinical psychology2025

The timing of symptom change and early treatment response in a self-guided digital treatment for obsessive-compulsive disorder.

Madelyne A Bisby, Bethany Wootton, Blake F Dear

Abstract read
In one paragraph

Article in The British journal of clinical psychology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Madelyne A BisbyeCentreClinic, School of Psychological Sciences, Macquarie University, Sydney, New South Wales, Australia.ORCID https://orcid.org/0000-0002-4354-3684
Bethany WoottoneCentreClinic, School of Psychological Sciences, Macquarie University, Sydney, New South Wales, Australia.ORCID https://orcid.org/0000-0001-9036-0699
Blake F DeareCentreClinic, School of Psychological Sciences, Macquarie University, Sydney, New South Wales, Australia.ORCID https://orcid.org/0000-0001-9324-3092

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveSelf-guided digital treatment is effective for many people with OCD-however, little is known about when during treatment people experience significant symptom reductions. In addition, there is substantial variability in the literature regarding what factors predict treatment responding in self-guided digital treatment for OCD. There is preliminary evidence to suggest that adults with OCD may show early treatment responding (i.e., significant symptom reductions within the first month of treatment) and that this early response could be associated with better post-treatment outcomes.

methodsIn a secondary analysis (n = 123), the current study examined the timing and magnitude of symptom change during self-guided digital CBT, the incidence of early response (at 4-weeks), and whether early treatment response predicted post-treatment response (at 8-weeks). These analyses were conducted for OCD symptoms (primary) and depression symptoms (secondary).

resultsResults indicated a gradual reduction in OCD and depression symptoms across treatment. Although fewer participants experienced an early response in OCD symptoms (22%) compared to depression symptoms (45%), early response was significantly associated with an increased likelihood of post-treatment response in both symptom domains.

conclusionsThese findings highlight that individuals with OCD symptoms may experience reductions in different symptom types at different points during treatment and that early response may be a prognostic factor for overall treatment response in this population across outcomes.

Indexed as

Cognitive Behavioral TherapyDepressionObsessive-Compulsive DisorderOutcome Assessment, Health CareAdultFemaleHumansMaleMiddle AgedTime FactorsTreatment OutcomeYoung Adultdigitalearly responseOCDpredictorstreatment outcome

Identifiers

PMID40186331
PMCPMC12506953

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.