Observational studyBMC oral health2025
Global burden and trends of oral disorders among adolescent and young adult (10-24 years old) from 1990 to 2021.
Observational study in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Oral health care challenges in individuals with severe mental illness: a qualitative meta-synthesis.Frontiers in oral health · 2025Pooled it
- Global, Regional, and National Burden of Caries Among Women of Childbearing Age From 1990 to 2021 and Prediction.International dental journal · 2026Article
- Mobile Applications for Oral Health Promotion in Adolescents: Efficacy, Challenges and Opportunities-A Comprehensive Review.Dentistry journal · 2026Review
- Selection for Function in Early Life: Implications for Early-Onset Pathologies.Evolutionary applications · 2026Article
- Dental caries beyond eradication: microbiome centered and equilibrium driven therapeutic strategies.Archives of microbiology · 2026Review
- Polyacrylic Acid concentrations on biomimetic remineralization in artificial enamel lesions.BMC oral health · 2026Article
- Global, Regional, and National Burden of Oral Diseases in Older Adults Aged 65 Years And Over.International dental journal · 2026Article
- Adolescent and young adult periodontitis: modifiable inflammatory pathways and risk stratification.Frontiers in medicine · 2026Review
- Lactobacillus sp. attenuates oral and hepatic alterations and decreases caspase-8 expression in ligature-induced periodontitis.Journal of applied oral science : revista FOB · 2026Article
- Expression of caspase-8 in non-alcoholic fatty liver disease related to ligature-induced periodontitis in rats.Journal of applied oral science : revista FOB · 2026Article
- Global burden and trends of oral disorders in adults aged 60 + (1990-2021) with projections to 2040.BMC oral health · 2025Article
- MALAT1/miR-181b axis mediates the anti-bacterial and anti-inflammatory effects of Galla chinensis in the progression of dental caries : Short title: mechanism of Galla chinensis in dental caries.Clinical oral investigations · 2025Article
- Global and regional burden and inequalities of oral conditions in children, adolescents, and young adults (0-39 years), 1990 to 2021.PLOS global public health · 2025Article
- Epidemiological trends and incidence prediction of periodontal disease based on the Global Burden of Disease study 2021.Frontiers in dental medicine · 2025Article
- Article
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Authors and funding
5 authors.
Funding
Abstract
objectiveTo determine the patterns and trends in the global, regional, and national burden of oral disorders among adolescents and young adults (AYA) from 1990 to 2021.
methodsThis is an epidemiological observational study that analyzed annual prevalence and disability-adjusted life years (DALYs) for oral disorders-including dental caries, periodontal disease, edentulism, and other oral conditions-among adolescents and young adults (ages 10-24) from 1990 to 2021. Data were sourced from the Global Burden of Disease Study (GBD) 2021. To assess temporal trends, the estimated annual percentage changes (EAPC) in age-standardized prevalence and DALY rates were calculated at global, regional, and national levels. The GBD 2021 also provides sociodemographic index (SDI) data across 204 countries and territories. Pearson correlation analyses were conducted to explore the relationships between age-standardized prevalence and DALY rates with the SDI and their respective EAPCs.
resultsGlobally, the prevalent cases of oral disorders increased by 17.1%, from 549.2 million in 1990 to 643.3 million in 2021, and DALYs rose by 22.2%, from 1.4 million in 1990 to 1.7 million in 2021. The overall age-standardized prevalence rate (EAPC = - 0.07 [95% CI, - 0.12 to - 0.03]) decreased, while the age-standardized DALY rate (EAPC = 0.06 [0.02 to 0.11]) increased over the same period. While the burden of dental caries declined, the burden of periodontitis and edentulism significantly increased. A negative correlation was observed between age-standardized prevalence and DALY rates and SDI, while a positive correlation was found between the EAPC of age-standardized DALY rates and SDI.
conclusionsThe prevalence and DALYs of oral disorders among AYA have risen over the past three decades, particularly due to the growing burden of periodontitis and edentulism. Notably, the most significant increases have been observed in Southern Latin America and South Asia. While the global decline in dental caries has led to a reduction in ASPR, the escalating burden of periodontal disease and edentulism remains a critical concern. These trends emphasize the urgent need for innovative prevention and intervention strategies to improve oral health for this demographic worldwide.
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