ArticleLipids in health and disease2025
Association between lipid accumulation product (LAP) index and self-reported oral health outcomes: a cross-sectional study.
Article in Lipids in health and disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundLipid Accumulation Product (LAP) is a biomarker associated with excessive lipid accumulation and various metabolic diseases. Despite the well-established link between oral and systemic health, the association between LAP and oral health remains largely unexplored.
methodsData from 7,124 participants aged over 18 years from the National Health and Nutrition Examination Survey (NHANES) between 2009 and 2014 were analyzed. Multivariate logistic regression models were applied to evaluate the independent association between LAP and self-reported oral health outcomes, adjusting for potential confounders.
resultsThere was a significant correlation between increasing LAP levels and deteriorating oral health status (β = 0.26, 95% CI: 0.20 to 0.32, P < 0.0001). Subgroup analyses revealed that the negative correlation between LAP and self-reported oral health outcomes was more pronounced in younger individuals and those with higher education levels. A non-linear relationship was identified, with oral health deteriorating significantly as LAP increased up to a threshold of 83, after which the relationship became non-significant.
conclusionsThis study demonstrates a robust association between LAP and self-reported oral health outcomes, suggesting that LAP could be a reliable indicator for assessing oral health status. The findings highlight the importance of targeted health interventions for populations with higher LAP indices to prevent oral health deterioration and potential systemic health issues.
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