ArticleBMC public health2025
The associations between serum carotenoids and hyperuricemia among U.S. National Health and Nutrition Examination Survey.
Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Associations between carotenoids and rheumatoid arthritis risk: evidence from two population-based studies.Nutrition journal · 2026Article
- Association between hyperuricemia and kidney stones in Southern China: a multicentre cross-sectional study.Frontiers in endocrinology · 2026Article
- Corn Steep Liquor as an Efficient Bioresource for Functional Components Production by Biotransformation Technology.Foods (Basel, Switzerland) · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHyperuricemia is a risk factor for various metabolic disorders. We aimed to investigate the association between serum carotenoid levels and hyperuricemia using data from the National Health and Nutrition Examination Survey (NHANES).
methodsWe conducted a cross-sectional analysis utilizing data from three specific NHANES cycles (2003-2004, 2005-2006, 2017-2018), containing the most complete serum carotenoid data from 12,253 participants aged 20 years and older. Serum carotenoids were quantified using high-performance liquid chromatography, while hyperuricemia was defined as serum uric acid levels ≥ 416 μmol/L (7.0 mg/dL) in men and ≥ 357 μmol/L (6.0 mg/dL) in women. Multivariable logistic regression models were employed to assess the relationship between carotenoids and hyperuricemia.
resultsThe mean age of participants was 50.1 ± 18.7 years, with a hyperuricemia prevalence of 20.5%. Higher serum carotenoids were associated with a lower prevalence of hyperuricemia, with each 1-unit increase in total carotenoids being inversely associated with hyperuricemia (odds ratio [OR] = 0.77, 95% confidence interval [CI]: 0.72-0.82) in multivariable analyses. Compared to participants with the lowest quartile, reduced ORs for hyperuricemia odds were observed for those with the highest quartile for total carotenoids (0.55 [0.47-0.64]), α-carotene (0.60 [0.52-0.71]), β-carotene (0.56 [0.48-0.65]), β-cryptoxanthin (0.58 [0.49-0.67]), trans-lycopene (0.75 [0.65-0.87]), cis-lycopene (0.83 [0.65-1.06]), total-lycopene (0.75 [0.64-0.87]), and lutein + zeaxanthin (0.66 [0.57-0.77]). Subgroup analyses indicated stronger associations among younger individuals, women, and those without any history of diabetes or cardiovascular disease.
conclusionsHigher serum carotenoid levels are associated with reduced odds of hyperuricemia. These results underscore the potential role of carotenoids in managing hyperuricemia and its related health complications.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.