Evidence map›Paper›PMID 40186176›Full record

Observational studyBMC pulmonary medicine2025

Prevalence and clinical impact of bacterial co-infection in chronaturenic pulmonary aspergillosis.

Fatma Tokgöz Akyıl, Sida Gösterici, Hülya Abalı, Derya Hırçın Cenger, Çiğdem Sabancı, Sinem Sökücü, Sedat Altın

Erratum issuedAbstract readObservational Study
In one paragraph

Observational study in BMC pulmonary medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Fatma Tokgöz AkyılDepartment of Chest Diseases, Yedikule Chest Diseases and Thoracic Surgery Training and Research Hospital, Zeytinburnu/İstanbul, Turkey. fatmatokgoz86@gmail.com.
Sida GöstericiDepartment of Chest Diseases, Yedikule Chest Diseases and Thoracic Surgery Training and Research Hospital, Zeytinburnu/İstanbul, Turkey.
Hülya AbalıDepartment of Chest Diseases, Yedikule Chest Diseases and Thoracic Surgery Training and Research Hospital, Zeytinburnu/İstanbul, Turkey.
Derya Hırçın CengerDepartment of Infectious Diseases, Yedikule Chest Diseases and Thoracic Surgery Training and Research Hospital, Zeytinburnu/İstanbul, Turkey.
Çiğdem SabancıDepartment of Chest Diseases, Yedikule Chest Diseases and Thoracic Surgery Training and Research Hospital, Zeytinburnu/İstanbul, Turkey.
Sinem SökücüDepartment of Chest Diseases, Yedikule Chest Diseases and Thoracic Surgery Training and Research Hospital, Zeytinburnu/İstanbul, Turkey.
Sedat AltınDepartment of Chest Diseases, Yedikule Chest Diseases and Thoracic Surgery Training and Research Hospital, Zeytinburnu/İstanbul, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe clinical significance of co-infection with chronic pulmonary aspergillosis (CPA) and bacteria is limited and has mostly been studied in specific patient groups. This study aims to investigate the incidence and prognostic impact of bacterial co-infection in patients with CPA.

methodsA single-center, retrospective, observational study was conducted between 2019 and 2024. Patients were categorized based on the presence of bacterial co-infection, and their demographics, potential underlying factors, and prognosis were analyzed.

resultsA total of 101 patients were included (mean age: 57 ± 13 years, 79 male). Bacterial co-infection was identified in 21 patients (21%). The most common bacterial pathogens at diagnosis were Pseudomonas aeruginosa (n = 6), Klebsiella pneumoniae (n = 5), Escherichia coli (n = 4), and Serratia marcescens (n = 4). Five patients had a history of prior bacterial colonization. At diagnosis, more than one bacterial species were identified in six patients. Sputum production and hypoxemic respiratory failure were more frequently observed in patients with bacterial co-infection. Systemic corticosteroid use was more common in the co-infected group. However, radiological findings and diagnostic procedures did not differ between the groups. Surgical interventions were more commonly performed in the non-co-infected group. During the follow-up, hospital admission rates, mortality, and overall survival were comparable between the two groups.

conclusionsBacterial co-infections are probable in CPA and follow-up results of both patient Groups may not differ. Timely diagnosis and close follow-up of these patients are probable key factors in these patients.

Indexed as

Bacterial InfectionsCoinfectionPulmonary AspergillosisAdultAgedFemaleHumansIncidenceMaleMiddle AgedPrevalencePrognosisPseudomonas aeruginosaRetrospective StudiesAspergillosisKlebsiella pneumoniaePneumoniaPseudomonas aeruginosa

Identifiers

PMID40186176
PMCPMC11971896

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.