Evidence map›Paper›PMID 40186162›Full record

ArticleBMC public health2025

Mercury poisoning in women and infants inhabiting the Gangetic plains of Bihar: risk assessment.

Arun Kumar, Radhika Agarwal, Kanhaiya Kumar, Nirmal Kumar Chayal, Govind Kumar, Rajiv Kumar, Mohammad Ali, Abhinav Srivastava, Siddhant Aryal, Tejasvi Pandey and 11 more

Abstract read
In one paragraph

Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Arun KumarMahavir Cancer Sansthan and Research Centre, Patna, Bihar, 801505, India. drarunk31@gmail.com.ORCID http://orcid.org/0000-0002-8946-5909
Radhika AgarwalLovely Professional University, Phagwara, Punjab, India.
Kanhaiya KumarMahavir Cancer Sansthan and Research Centre, Patna, Bihar, 801505, India.
Nirmal Kumar ChayalAmity University, Jaipur, Rajasthan, India.
Govind KumarIndian Institute of Technology- Bombay, Mumbai, Maharashtra, India.
Rajiv KumarMahavir Cancer Sansthan and Research Centre, Patna, Bihar, 801505, India.
Mohammad AliMahavir Cancer Sansthan and Research Centre, Patna, Bihar, 801505, India.
Abhinav SrivastavaMahavir Cancer Sansthan and Research Centre, Patna, Bihar, 801505, India.
Siddhant AryalMahavir Cancer Sansthan and Research Centre, Patna, Bihar, 801505, India.
Tejasvi PandeyLovely Professional University, Phagwara, Punjab, India.
Kumar Sambhav VermaAmity University, Jaipur, Rajasthan, India.
Dhruv KumarUPES, Dehradun, Uttarakhand, India.
Rahul Laxman GajbhiyeNational Institute of Pharmaceutical Education and Research , Hajipur, Vaishali, Bihar, India.
Sameer DhingraNational Institute of Pharmaceutical Education and Research , Hajipur, Vaishali, Bihar, India.
Naresh PothurajuNational Institute of Pharmaceutical Education and Research , Hajipur, Vaishali, Bihar, India.
Ramalingam PeramanNational Institute of Pharmaceutical Education and Research , Hajipur, Vaishali, Bihar, India.
Akhouri BishwapriyaGeological Survey of India, Ranchi, Jharkhand, India.
Ranbir NandanDepartment of Geology, Patna University, Patna, Bihar, India.
Ashok SharmaAll India Institute of Medical Sciences, New Delhi, India.
Manisha SinghMahavir Cancer Sansthan and Research Centre, Patna, Bihar, 801505, India.
Ashok Kumar GhoshMahavir Cancer Sansthan and Research Centre, Patna, Bihar, 801505, India.

Funding

Indian Council of Medical Research ICMR F.No. 5/10/FR/79/2020-RBMCH, Dated. 09/08/2021
6 · The paper itself

Abstract

Mercury is a persistent, bio-accumulative, and hazardous contaminant. When released into the environment, it accumulates in water sediments, converting it to poisonous methylmercury that enters the food chain. The present study was carried out in habitations from the 11 districts of Bihar (India). In the study, n = 224 lactating women and their infants n = 172 infants participated. After obtaining the written informed consent, their breast milk, urine, and blood were collected for mercury estimation. The breastmilk content was measured in n = 181 subjects, in which 74% women had their breastmilk higher than the WHO permissible limit (< 1.7 μg/L), while 26% of the women had their breast milk below the permissible limit. The blood mercury content showed that 19% subjects had mercury content above the permissible limit [20 μg/L]. In urine mercury estimation, 49% women had mercury content above the permissible limit [10 μg/L], while, 51% women had the mercury content below the permissible limit. In the child's urine, 54% infants had their mercury content in urine above the permissible limit [10 μg/L] while 46% infants had content below the permissible limit. The study indicates that 20% of infants had the complete accumulation of mercury in their body which is highly toxic for them. However, the mercury content in the food (wheat) had the contamination with in the permissible limit [100 μg/kg]. There was a significant correlation found between the breastmilk and child's urine and mother's urine. The HQ study also correlates the mercury poisoning effect with 100% of the mother's and 66% of the infants exceeding the limit of non-carcinogenic risk. The Monte Carlo and multivariate study correlates the high health risk in the studied population due to mercury poisoning. The entire study concludes that population inhabitation in the Gangetic plains of Bihar are exposed to mercury poisoning which may be due to geogenic or anthropogenic sources. But, the levels of mercury contamination above the permissible limit could lead to neurogenerative changes in the lactating mothers and their infants. To control the present problem medical intervention is immediately required.

Indexed as

Environmental ExposureMercuryMercury PoisoningAdultFemaleHumansIndiaInfantInfant, NewbornMilk, HumanRisk AssessmentYoung AdultMercuryBreastmilkGeospatial mappingInfantsLactating mothersMercury poisoning

Identifiers

PMID40186162
PMCPMC11971891

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.