Evidence map›Paper›PMID 40186159›Full record

ArticleBMC psychiatry2025

Changes in network centrality of anxiety and depression symptoms associated with childhood trauma among Chinese college students.

Yuanmei Tao, Huanhuan Fan, Min Wang, Yushun Yan, Yikai Dou, Liansheng Zhao, Rongjun Ni, Jinxue Wei, Xiao Yang, Xiaohong Ma

Abstract read
In one paragraph

Article in BMC psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yuanmei Tao *Mental Health Center, Institute of Psychiatry, West China Hospital, Sichuan University, Guoxue Alley 37, Chengdu, Sichuan, 610041, China.
Huanhuan Fan *Mental Health Center, Institute of Psychiatry, West China Hospital, Sichuan University, Guoxue Alley 37, Chengdu, Sichuan, 610041, China.
Min WangMental Health Center, Institute of Psychiatry, West China Hospital, Sichuan University, Guoxue Alley 37, Chengdu, Sichuan, 610041, China.
Yushun YanMental Health Center, Institute of Psychiatry, West China Hospital, Sichuan University, Guoxue Alley 37, Chengdu, Sichuan, 610041, China.
Yikai DouMental Health Center, Institute of Psychiatry, West China Hospital, Sichuan University, Guoxue Alley 37, Chengdu, Sichuan, 610041, China.
Liansheng ZhaoMental Health Center, Institute of Psychiatry, West China Hospital, Sichuan University, Guoxue Alley 37, Chengdu, Sichuan, 610041, China.
Rongjun NiMental Health Center, Institute of Psychiatry, West China Hospital, Sichuan University, Guoxue Alley 37, Chengdu, Sichuan, 610041, China.
Jinxue WeiMental Health Center, Institute of Psychiatry, West China Hospital, Sichuan University, Guoxue Alley 37, Chengdu, Sichuan, 610041, China.
Xiao YangMental Health Center, Institute of Psychiatry, West China Hospital, Sichuan University, Guoxue Alley 37, Chengdu, Sichuan, 610041, China. yangxiao@wchscu.cn.
Xiaohong MaMental Health Center, Institute of Psychiatry, West China Hospital, Sichuan University, Guoxue Alley 37, Chengdu, Sichuan, 610041, China. maxiaohong@scu.edu.cn.

Funding

the 135 Project from West China Hospital of Sichuan University 2023HXFH006the 135 Project from West China Hospital of Sichuan University 2023HXFH040the Ministry of Science and Technology of the People's Republic of China 2022ZD0211700the Postdoctoral Fellowship Program of CPSF GZC2023180the Postdoctoral Research Fund of West China Hospital,Sichuan University 2024HXBH046the Postdoctoral Research Fund of West China Hospital,Sichuan University 2024HXBH135the Sichuan Science and Technology Program 2024NSFSC1559
6 · The paper itself

Abstract

backgroundChildhood trauma is strongly linked to anxiety and depression, significantly increasing the risk of negative outcomes in adulthood. This study employed network analysis to investigate the complex interplay of anxiety and depression symptoms among Chinese college students, focusing on identifying the core symptoms most directly affected by childhood trauma and those exerting the greatest influence on others.

methodsData were collected from December 2020 to January 2021 from 2,266 college students at 16 institutions in southwestern and eastern coastal China. Depression, anxiety, and childhood trauma were assessed using the Patient Health Questionnaire-9, Generalized Anxiety Disorder-7, and Childhood Trauma Questionnaire-28, respectively. Separate symptom networks were constructed for participants with and without childhood trauma experiences. Central indices were employed to identify the central symptom within each network. The accuracy and stability of the networks were then evaluated. Finally, a network comparison test was used to analyze differences in network properties between the trauma and non-trauma groups.

resultsLoss of Energy and Worry too much were the central symptoms in the non-trauma group, while anhedonia and nervousness were the central symptoms in the trauma group. There was a significant difference in the global strength of the network between the trauma group and the non-trauma group (p

conclusionsThis study demonstrates the profound impact of childhood trauma on the central symptoms of anxiety and depression in college students. Further research is warranted to investigate the specific pathways through which these symptoms develop, with the goal of developing targeted interventions for this vulnerable population.

Indexed as

AnxietyDepressionStudentsAdolescentAdultChinaFemaleHumansMaleUniversitiesYoung AdultAnxietyChildhood traumaCollege studentsDepressionNetwork analysis

Identifiers

PMID40186159
PMCPMC11969975

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.