SynthesisBMC pediatrics2025
Treatment and prognosis of pelvic-related urethral injuries in children: a 20-year single-center study and systematic review.
Synthesis in BMC pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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1 citing paper in PubMed.
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11 authors.
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Abstract
backgroundManagement of pelvic fracture-related urethral injury (PFUI) in children remains debated due to various complications. Patients typically receive either primary realignment (PR) or suprapubic cystostomy with delayed urethroplasty (SCDU), but optimal outcomes are unclear. This study evaluates these two surgical techniques by reviewing 20 years of case data and existing literature.
methodsWe retrospectively analyzed patients treated for PFUI from 2004 to 2023, with a median follow-up of 2 years (1-15 years). Additionally, we performed a meta-analysis of relevant literature, searching PubMed, Web of Science, and Cochrane databases. Eight studies, including ours, were included in the analysis.
resultsSixty-eight boys with PFUI (median age: 7.3 years; range: 4.8-10.8) underwent PR (39) or SCDU (29). Postoperative complications-urethral strictures, urinary incontinence, calculus, infections, and erectile dysfunction-occurred in PR vs. SCDU groups as follows: 38.5% vs. 51.7% (p = 0.276); 12.8% vs. 3.45% (p = 0.360); 7.7% vs. 13.8% (p = 0.678); 56.4% vs. 93.1% (p < 0.001); and15.4% vs. 3.5% (p = 0.231), respectively. PR was associated with lower costs and higher quality of life. The meta-analysis of eight studies involving 432 patients showed no significant differences between PR and SCDU in urethral stricture rates (OR = 0.60, 95% CI 0.33-1.10, p = 0.10), urinary incontinence (OR = 0.94, 95% CI 0.52-1.70, p = 0.84), and erectile dysfunction (OR = 0.85, 95% CI 0.41-1.76, p = 0.65).
conclusionThere was no difference in complications between the two surgical modalities at long-term follow-up, however, PR presents more advantages in reduce operative times, frequency of postoperative infections, cost, and long-term quality of life. CLINICAL TRIAL NUMBER: Not applicable.
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