Evidence map›Paper›PMID 40186132›Full record

Trial reportBMC musculoskeletal disorders2025

Low frequency physiotherapy on joint health, hemarthrosis, walking, balance and reaction time in hemophilic arthropathy: a controlled trial.

Ayse Merve Tat, Necati Muhammed Tat, Serbay Sekeroz, Meryem Buke, Kamuran Karaman

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC musculoskeletal disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06331091 (The Effectiveness of Low Frequency Comprehensive Physiotherapy Combined With Home Exercise on Joint Health, Frequency of Hemartrosis, Dynamic Balance and Reaction Time in Hemophilic Arthropthy), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06331091 nacompletednot on this map

The Effectiveness of Low Frequency Comprehensive Physiotherapy Combined With Home Exercise on Joint Health, Frequency of Hemartrosis, Dynamic Balance and Reaction Time in Hemophilic Arthropthy

TypeinterventionalSponsorYuzuncu Yil UniversityRan2022 to 2024Enrolled21ConditionsHemophilia ArthropathyArmsHome exercise, Manual therapy, Neuromuscular electrical stimulation, Supervised exercise
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ayse Merve TatFaculty of Health Sciences, Department of Physiotherapy and Rehabilitation, Van Yüzüncü Yıl University, Van, Turkey. aysemervetat@yyu.edu.tr.ORCID http://orcid.org/0000-0001-6232-1860
Necati Muhammed TatFaculty of Health Sciences, Department of Physiotherapy and Rehabilitation, Van Yüzüncü Yıl University, Van, Turkey.ORCID http://orcid.org/0000-0001-5858-2718
Serbay SekerozFaculty of Health Sciences, Department of Physiotherapy and Rehabilitation, Van Yüzüncü Yıl University, Van, Turkey.ORCID http://orcid.org/0000-0001-8921-8492
Meryem BukeFaculty of Health Sciences, Department of Physiotherapy and Rehabilitation, Van Yüzüncü Yıl University, Van, Turkey.ORCID http://orcid.org/0000-0002-5700-9407
Kamuran KaramanFaculty of Medicine, Van Yüzüncü Yıl University, Van, Turkey.ORCID http://orcid.org/0000-0003-2991-3551

Funding

Van Yüzüncü Yıl University Scientific Research Projects Coordination Unit TSG-2022-10064
6 · The paper itself

Abstract

backgroundPhysiotherapy is recommended for people with hemophilic arthropathy (PwHA) to improve musculoskeletal health and is typically administered in 2 or 3 sessions per week. We aimed to investigate the effects of once a week comprehensive physiotherapy and home exercise on musculoskeletal system of PwHA.

methodsIn this study 19 young PwHA with knee and/or ankle were non-randomly divided into two groups: The Home Exercise Group (HEG) and the Comprehensive Physiotherapy Group (CPG). Joint health was evaluated with the Hemophilia Joint Health Score (HJHS), muscle strength (MS) with manual muscle tester, range of motion (ROM) with universal goniometer, pain with Numerical Pain Scale (NPS). The following functional tests were used: 6 min Walking Test (6MWT) for walking capacity, Functional Reach Test (FRT) for dynamic balance and Fitlight

resultsCompared with the HEG, the CPG significantly ameliorated for NPS, FoH, HJHS, VMRT (time and mean), 6MWT, all MS and several ROMs. CPG significantly improved in all outcomes except for 1 ROM. The HEG significantly improved in FoH, HJHS, VMRT (time), 6MWT and MS, but not in the ROMs.

conclusionComprehensive physiotherapy once a week and continuing home exercise significantly improve joint health, functionality and balance, and reduce pain and hemarthrosis in PwHA.

trial registrationThe study was registered at Clinicaltrials.gov (Study ID NCT06331091, retrospectively registered).

Indexed as

Exercise TherapyHemarthrosisHemophilia APhysical Therapy ModalitiesPostural BalanceWalkingAdolescentAdultHumansKnee JointMaleMuscle StrengthRange of Motion, ArticularTreatment OutcomeYoung AdultArthropathyExerciseHemarthrosisHemophiliaPhysiotherapyReaction time

Identifiers

PMID40186132
PMCPMC11971827

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.