Evidence map›Paper›PMID 40186060›Full record

Observational studyInternational ophthalmology2025

Pain management in lacrimal lavage: insights from a comparative study.

Emine Savran Elibol, Serap Karaca, Ceren Cemre Bayca, Fatih Savran

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In one paragraph

Observational study in International ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Emine Savran ElibolDepartment of Ophthalmology, BahçEşEhir University, Istanbul, Turkey. emine.savranelibol@bau.edu.tr.ORCID http://orcid.org/0000-0001-8988-8832
Serap KaracaDepartment of Ophthalmology, Goztepe Prof. Dr. Süleyman YalçıN City Hospital, Istanbul, Turkey.ORCID http://orcid.org/0000-0003-0325-2804
Ceren Cemre BaycaDepartment of Ophthalmology, Faculty of Medicine, Istanbul Medeniyet University, Istanbul, Turkey.ORCID http://orcid.org/0000-0001-9810-370X
Fatih SavranDepartment of Otorhinolaringology, Private Istanbul Sancaktepe Bölge Hospital, Istanbul, Turkey.ORCID http://orcid.org/0000-0001-5338-8641

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe lacrimal lavage test commonly assesses lacrimal obstruction but can cause discomfort. This study compares pain scores during lacrimal lavage for the first and second eye, examines differences between eyes with and without nasolacrimal duct obstruction, and evaluates lidocaine versus saline for pain relief. MATERIALS AND

methodsThis cross-sectional observational study was conducted at the Ophthalmology Department of a University Hospital from October to November 2024 and included 252 eyes from 126 patients with epiphora who underwent nasolacrimal lavage. Lacrimal irrigation was performed using a 23-G blunt cannula with saline on one side and lidocaine on the other. Pain was assessed using the Visual Analog Scale (VAS).

resultsThere was no significant difference (p = 0.26) in VAS scores between the saline and lidocaine irrigation sides. However, the VAS score for the lavage performed on the first side was significantly higher (p = 0.047) than the second side. Additionally, female patients reported significantly higher VAS scores compared to male patients (p = 0.001). In patients with dacryostenosis, the VAS score on the side with nasolacrimal duct obstruction was significantly higher (p = 0.008) compared to the side without NLDO.

conclusionThis study shows that lacrimal lavage is a painful procedure for assessing the nasolacrimal duct. Lidocaine was ineffective in reducing pain, with most discomfort caused by fluid pressure. Higher pain scores were observed in obstructed ducts and during the first procedure, likely due to anxiety. Women reported greater pain than men, underscoring the need to address gender differences in pain management.

Indexed as

Eye PainLacrimal Duct ObstructionNasolacrimal DuctPain ManagementTherapeutic IrrigationAdultAgedAnesthetics, LocalCross-Sectional StudiesFemaleHumansLidocaineMaleMiddle AgedPain MeasurementAnesthetics, LocalLidocaineLacrimal lavageNasolacrimal duct obstructionSyringingVisual analogue scale

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.