ArticleProbiotics and antimicrobial proteins2026
Unraveling the Bioactivities and Immunomodulatory Potential of Postbiotics Derived from Bacillus subtilis and B. amyloliquefaciens for Aquaculture.
Article in Probiotics and antimicrobial proteins, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
7 citing papers in PubMed.
- Beyond Probiotics: Postbiotics for Healthy Aquaculture.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Antibiofilm, Antimicrobial, and Limited Ammonia-Reduction Activities of Bacillus cereus-Group Isolates From Hot Spring Sediment and Rubber Latex Serum for Aquaculture Water Management.Water environment research : a research publication of the Water Environment Federation · 2026Article
- Postbiotics as Multifunctional Bioactives: Mechanistic Insights and Translational Applications in Host Physiology and Microbial Ecosystem Modulation.Microorganisms · 2026Review
- Integrated Metabolomic and Genomic Analysis of the Antibacterial Mechanism of Postbiotics Derived fromFoods (Basel, Switzerland) · 2026Article
- Probiotic Properties In Vitro ofMicroorganisms · 2025Article
- Postbiotics of Marine Origin and Their Therapeutic Application.Marine drugs · 2025Review
- Microbiome engineering to enhance disease resistance in aquaculture: current strategies and future directions.Frontiers in microbiology · 2025Review
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Postbiotics are molecules or soluble factors released as a result of a probiotic's metabolic activity. Their use in enhancing the growth, health, and disease resistance of aquatic animals has gained considerable attention in aquaculture. The present investigation was designed to assess the beneficial effects of postbiotic products derived from two probiotic strains, Bacillus subtilis and B. amyloliquefaciens. Postbiotics from B. subtilis exhibited significantly greater (p < 0.05) antibacterial activity against various pathogenic bacterial strains, more robust antagonistic growth kinetics, stronger anti-virulence potential, enhanced inhibition of biofilm formation, and increased antioxidant activity compared to those from B. amyloliquefaciens. Additionally, B. subtilis postbiotics triggered a significant (p < 0.05) cellular immune response, including higher myeloperoxidase activity, leucocyte proliferation, and production of nitric oxide and superoxide anions, along with a notable upregulation of immune-related gene expression (IL-1β, IL-10, IFN-γ, and TNF-α) in the head kidney leucocytes of Labeo rohita. A challenge test on L. rohita fingerlings confirmed the safety of B. subtilis postbiotics. These findings highlight the anti-pathogenic, immunostimulatory, and disease-resistant properties of B. subtilis postbiotics, suggesting their promising application in aquaculture.
Indexed as
Identifiers
40186049What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.