Evidence map›Paper›PMID 40185971›Full record

ArticleEuropean child & adolescent psychiatry2025

Trends in antipsychotic treatment of children and adolescents in Israel from post-mental health reform to post-COVID19 pandemic (2015-2023).

Rachel Nega, Ron Walfisch, Michal Taler, Martin Efron, Nurit El Bar, Revital Perlov Gavze, Liat Lev-Shalem, Gilad Bodenheimer, Yonatan Bilu, Doron Gothelf

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Article in European child & adolescent psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Rachel NegaThe Child Psychiatry Division, Sheba Medical Center, Ramat Gan, Israel.
Ron WalfischThe Child Psychiatry Division, Sheba Medical Center, Ramat Gan, Israel.
Michal TalerThe Child Psychiatry Division, Sheba Medical Center, Ramat Gan, Israel.
Martin EfronThe Child Psychiatry Division, Sheba Medical Center, Ramat Gan, Israel.
Nurit El BarMaccabi Health Care Services, Tel Aviv, Israel.
Revital Perlov GavzeMaccabi Health Care Services, Tel Aviv, Israel.
Liat Lev-ShalemMaccabi Health Care Services, Tel Aviv, Israel.
Gilad BodenheimerMaccabi Health Care Services, Tel Aviv, Israel.
Yonatan BiluKI Research Institute, Kfar Malal, Israel.
Doron GothelfThe Child Psychiatry Division, Sheba Medical Center, Ramat Gan, Israel. gothelf@tauex.tau.ac.il.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study investigates the patterns of antipsychotic drug dispensations among children and adolescents from 2015 to 2023, with a focus on the impact of introducing national health reform (2015) and the COVID-19 pandemic. Data from Maccabi Healthcare Services, encompassing 1,105,439 individuals aged 6-18 years, were analyzed using a retrospective cohort study. We investigated the incidence rates of antipsychotic prescriptions by age, sex, socioeconomic status, and geographical region. During the study period, there was a 15% overall increase in antipsychotics prescriptions. Higher prescription rates were observed among boys aged 6-11 years and girls aged 14-18 years. Significant increases in prescriptions were observed in the year immediately following the mental health reform and the COVID-19 pandemic. Low socioeconomic status and peripheral regions exhibited higher and increasing prescription rates. Seasonal patterns revealed peaks in the fourth quarter of each year. The study highlights an overall increase in antipsychotic prescriptions, influenced by policy changes and the pandemic. Inequality in prescription rates by socioeconomic status and geographical location underscores the need for targeted mental health interventions. The findings also suggest enduring changes in the utilization of antipsychotic medications among youth, which may reflect broader impacts of the COVID-19 pandemic on mental health care needs.

Indexed as

Antipsychotic AgentsCOVID-19Drug PrescriptionsHealth Care ReformMental DisordersAdolescentChildFemaleHumansIsraelMaleRetrospective StudiesAntipsychotic AgentsAdolescentsAntipsychoticsChildrenCOVID-19Prescription trends socioeconomic status

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.