Evidence map›Paper›PMID 40185957›Full record

ArticleAIDS and behavior2025

Seroprevalence and Risk Factors of STIs among Rejected Blood Donors at the National Blood Transfusion Service in Angola.

Cruz S Sebastião, Domingos Jandondo, João Vigário, Felícia António, Joana M K Sebastião, Maria L S Silva, Victor Pimentel, Ana Abecasis, Euclides Sacomboio, Jocelyne Neto Vasconcelos and 1 more

Abstract read
In one paragraph

Article in AIDS and behavior, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Cruz S SebastiãoCentro Nacional de Investigação Científica (CNIC), Luanda, Angola. cruzdossantos10@gmail.com.ORCID http://orcid.org/0000-0003-1232-0119
Domingos JandondoCentro de Investigação em Saúde de Angola (CISA)|Instituto Nacional de Investigação em Saúde (INIS), Luanda, Angola.
João VigárioInstituto Nacional de Sangue (INS), Ministério da Saúde, Luanda, Angola.
Felícia AntónioInstituto Nacional de Sangue (INS), Ministério da Saúde, Luanda, Angola.
Joana M K SebastiãoCentro de Investigação em Saúde de Angola (CISA)|Instituto Nacional de Investigação em Saúde (INIS), Luanda, Angola.
Maria L S SilvaFaculdade de Medicina (FM), Universidade Katyavala Bwila (UKB), Benguela, Angola.
Victor PimentelGlobal Health and Tropical Medicine, Associate Laboratory in Translation and Innovation Towards Global Health, GHTM, LA-REAL, Instituto de Higiene e Medicina Tropical, IHMT, Universidade NOVA de Lisboa, UNL, Rua da Junqueira 100, Lisboa, 1349-008, Portugal.
Ana AbecasisGlobal Health and Tropical Medicine, Associate Laboratory in Translation and Innovation Towards Global Health, GHTM, LA-REAL, Instituto de Higiene e Medicina Tropical, IHMT, Universidade NOVA de Lisboa, UNL, Rua da Junqueira 100, Lisboa, 1349-008, Portugal.
Euclides SacomboioInstituto de Ciências da Saúde (ICISA), Universidade Agostinho Neto (UAN), Luanda, Angola.
Jocelyne Neto VasconcelosCentro de Investigação em Saúde de Angola (CISA)|Instituto Nacional de Investigação em Saúde (INIS), Luanda, Angola.
Joana MoraisCentro de Investigação em Saúde de Angola (CISA)|Instituto Nacional de Investigação em Saúde (INIS), Luanda, Angola.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sexually transmitted infections (STIs) are a global health concern. Blood donation centres employ comprehensive screening measures to identify donors with STIs, such as HIV, HBV, HCV, and syphilis, which can also transmitted through blood transfusions. Herein, we investigated the seroprevalence of STIs and demographic determinants related to multiple infections among rejected blood donors at the National Blood Transfusion Service (NBTS) in Angola. This was a cross-sectional study conducted with 1885 rejected blood donors serologically screened for anti-HBsAg, anti-HCV, anti-HIV, and anti-TP during pre-donation screening at the NBTS, located in Luanda, the capital city of Angola, between March 2022 to July 2023. Overall, HIV (11.2%), HBsAg (71.7%), HCV (9.30%), and Syphilis (8.80%) were detected. The multiple infection rate was 2.30%. HIV and syphilis were associated with age (p < 0.05). HBV was related to age, areas of residence, and occupation (p < 0.05). HCV was related to areas of residence and educational level (p < 0.05). No relationship was observed between demographic characteristics with multiple infections (p > 0.05). Individuals aged over 40 years (OR: 2.48, p = 0.393), males (OR: 1.33, p = 0.639), non-urbanized regions (OR: 1.18, p = 0.594), low educational level (OR: 3.46, p = 0.222), and employed (OR: 1.34, p = 0.423), were more likely to have multiple infections. Our results demonstrate a high rate of circulation of STIs among blood donation candidates in Luanda. HBV was the main reason for the rejection of candidates. However, nucleic acid-based screening techniques should be considered to ensure better quality screening for occult infections in blood donor candidates.

Indexed as

Blood DonorsSexually Transmitted DiseasesSyphilisAdolescentAdultAngolaCross-Sectional StudiesFemaleHepatitis BHepatitis CHIV InfectionsHumansMaleMiddle AgedRisk FactorsSeroepidemiologic StudiesAngolaEpidemiologySeroprevalenceSexual transmitted infectionsTransfusion medicine

Identifiers

PMID40185957
PMCPMC12378782

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.