Evidence map›Paper›PMID 40185612›Full record

ArticleJACC. Case reports2025

Spinal Cord Infarction as a Complication of VA-ECMO With Microaxial Flow Pump in Cardiogenic Shock.

Arushi Singh, Syed Zain Ali, Kelly A Drozdowicz, Amit Alam, Randal I Goldberg, Justin C Chan, Marzia Leacche, Nader Moazami, Alex Reyentovich, Bernard S Kadosh

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Arushi SinghLeon H. Charney Division of Cardiology, New York University Grossman School of Medicine, New York, New York, USA. Electronic address: Arushi.singh@nyulangone.org.
Syed Zain AliLeon H. Charney Division of Cardiology, New York University Grossman School of Medicine, New York, New York, USA.
Kelly A DrozdowiczDepartment of Cardiothoracic Surgery, New York University Grossman School of Medicine, New York, New York, USA.
Amit AlamLeon H. Charney Division of Cardiology, New York University Grossman School of Medicine, New York, New York, USA.
Randal I GoldbergLeon H. Charney Division of Cardiology, New York University Grossman School of Medicine, New York, New York, USA.
Justin C ChanDepartment of Cardiothoracic Surgery, New York University Grossman School of Medicine, New York, New York, USA.
Marzia LeaccheDepartment of Cardiothoracic Surgery, New York University Grossman School of Medicine, New York, New York, USA.
Nader MoazamiDepartment of Cardiothoracic Surgery, New York University Grossman School of Medicine, New York, New York, USA.
Alex ReyentovichLeon H. Charney Division of Cardiology, New York University Grossman School of Medicine, New York, New York, USA.
Bernard S KadoshLeon H. Charney Division of Cardiology, New York University Grossman School of Medicine, New York, New York, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

clinical conditionThe authors present the case of a young man who presented with cardiogenic shock requiring venoarterial extracorporeal membrane oxygenation and microaxial flow pump complicated by acute spinal cord infarction (SCI) leading to bilateral lower extremity paraplegia. KEY QUESTIONS: The key questions included the following: 1) What is the incidence and pathophysiology for SCI with mechanical circulatory support (MCS)?; 2) Which configurations of MCS carry a greater risk of SCI? How do we approach MCS escalation, recognizing that with each device we carry additive risk of complications?; 3) What data guide anticoagulation strategies for MCS?; and 4) What strategies can we implement to support patients who have suffered SCI from MCS? OUTCOME: Our patient was transitioned to a right ventricular assist device with Impella 5.5 as a bridge to therapy, and underwent cardiac transplantation 4 weeks after presentation with ongoing inpatient rehabilitation. TAKE-HOME MESSAGES: Contemporary MCS carries a small but significant risk of SCI which is often irreversible. More data are required to guide anticoagulation strategies for MCS and mitigate risk.

Indexed as

cardiac transplantationcardiogenic shockImpellamechanical circulatory supportspinal cord infarctionVA-ECMO

Identifiers

PMID40185612
PMCPMC12046831

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.