ArticleJACC. Case reports2025
Transesophageal Echocardiogram With Isoproterenol to Unmask Previously Occult Left Ventricular Outflow Tract Obstruction.
Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Unexplained Syncope in Athletes: Unmasking Left Ventricular Outflow Tract Obstruction.JACC. Case reports · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Thorough and accurate evaluation of left ventricular outflow tract (LVOT) obstruction is critical in the assessment and management of patients with hypertrophic cardiomyopathy (HCM). Although Doppler echocardiography has become the initial modality to assess LVOT obstruction, it may not identify all patients with labile obstruction. In patients with a high clinical suspicion of LVOT obstruction, further provocative testing is needed. In HCM patients with poor transthoracic echocardiogram windows or who are unable to exercise, isoproterenol-guided transesophageal echocardiogram (TEE) remains a viable option to assess for systolic anterior motion (SAM) and LVOT obstruction. We report 4 individuals in whom there was no obvious SAM or LVOT obstruction at rest but who had severe LVOT obstruction unmasked by isoproterenol-guided TEE.
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Registered trials
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