Evidence map›Paper›PMID 40185597›Full record

ArticleJACC. Case reports2025

Massive Myocardial Calcification.

Mehran Babady, Charalampia Maltsinioti, Ermal Limaj, Oliver Bruder, Christina Karamarkou

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mehran BabadyDepartment of Cardiology and Angiology, Elisabeth Hospital Essen, Essen, Germany. Electronic address: m.babady@contilia.de.
Charalampia MaltsiniotiDepartment of Cardiology and Angiology, Elisabeth Hospital Essen, Essen, Germany.
Ermal LimajDepartment of Cardiology and Angiology, Elisabeth Hospital Essen, Essen, Germany.
Oliver BruderDepartment of Cardiology and Angiology, Elisabeth Hospital Essen, Essen, Germany.
Christina KaramarkouDepartment of Cardiology and Angiology, Elisabeth Hospital Essen, Essen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMassive myocardial calcification is an extremely rare condition with diverse etiologies, often requiring multimodality imaging for diagnosis. CASE SUMMARY: A 73-year-old woman with coronary artery disease and a history of ovarian carcinoma presented with dizziness and dyspnea. Echocardiography revealed a large floating structure on the anterior mitral leaflet, left ventricular hypertrophy, and extensive myocardial calcification. Preoperative imaging confirmed calcifications, and surgery included decalcification, subvalvular myectomy, and aortic valve replacement. Histology revealed fibrosis and scarring. Four years later, she developed pulmonary hypertension, increased calcification, and right ventricular dysfunction. Despite thorough evaluation, the etiology of the calcification remained unclear, with hypertrophic cardiomyopathy considered a probable underlying condition. DISCUSSION: This case highlights a rare presentation of myocardial calcification, emphasizing the value of multimodality imaging and comprehensive diagnostic workup. It contributes to the limited literature on the condition and its management challenges. TAKE-HOME MESSAGES: Multimodality imaging and a systematic approach are vital for diagnosing and managing rare cardiac conditions like massive myocardial calcification.

Indexed as

cardiomyopathycomputed tomographydisorders of calcium metabolismechocardiographypulmonary hypertension

Identifiers

PMID40185597
PMCPMC12046806

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.