Evidence map›Paper›PMID 40184901›Full record

Trial reportGeriatric nursing (New York, N.Y.)

Immediate and long-term effects of transcranial direct current stimulation on pain relief in older adults with Alzheimer's disease and related dementias: A pilot study.

Chiyoung Lee, Juyoung Park, Mindy Fain, James E Galvin, Lindsey Park, Hyochol Ahn

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Geriatric nursing (New York, N.Y.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chiyoung LeeThe University of Arizona College of Nursing, Tucson, AZ, USA.
Juyoung ParkThe University of Arizona College of Nursing, Tucson, AZ, USA. Electronic address: jpark13@arizona.edu.
Mindy FainThe University of Arizona College of Medicine, Division of General Internal Medicine, Geriatrics and Palliative Medicine, Tucson, AZ, USA; University of Arizona Center on Aging, Tucson, AZ, USA.
James E GalvinUniversity of Miami Miller School of Medicine, Department of Neurology, Comprehensive Center for Brain Health, Miami, FL, USA.
Lindsey ParkThe University of Arizona College of Nursing, Tucson, AZ, USA.
Hyochol AhnThe University of Arizona College of Nursing, Tucson, AZ, USA.

Funding

Pain-related Brain Mechanisms for Pain Catastrophizing Behavior in Response to Home-based Mindfulness-based Meditation Paired with Transcranial Direct Current StimulationR01NR019051 · NINR · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI AHN, HYOCHOL · 2020 to 2025
$2.9M
Self-Administered Transcranial Direct Current Stimulation for Pain in Older Adults with Knee Osteoarthritis: A Phase II Randomized Sham-Controlled TrialR15NR018050 · NINR · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MATHIS, KENNETH B · 2019 to 2020
$618k
NINR NIH HHS R01 NR019051NINR NIH HHS R15 NR018050
6 · The paper itself

Abstract

We simultaneously assessed the impact of transcranial direct current stimulation (tDCS) on mitigating both self-reported pain and pain behaviors to more objectively explore its effects in older adults with Alzheimer's disease and related dementias. The analysis investigated 40 participants randomly (1:1) subjected to active and sham tDCS for 20 min on 5 consecutive days. Multi-group latent transition analysis enabled the simultaneous evaluation of both pain domains in a single model and analysis of their changes as a function of intervention exposure by modeling the transition probabilities of latent classes and comparing these changes between groups. Two pain categories ("high pain" and "low pain") were identified based on the numeric rating scale and mobilization-observation-behavior-intensity-dementia scale scores. Overall, tDCS demonstrated better effects in helping participants transition to a "low pain" status during and after the intervention (∼3 months) compared with sham stimulation, demonstrating its immediate and enduring effects.

Indexed as

Alzheimer DiseaseDementiaPainPain ManagementTranscranial Direct Current StimulationAgedAged, 80 and overFemaleHumansMalePain MeasurementPilot ProjectsAlzheimer's disease and related dementiasLatent transition analysisPainTranscranial direct current stimulation

Identifiers

PMID40184901
PMCPMC12162193

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.