ArticleInternational dental journal2025
Craniofacial, Dental, and Upper Airway Morphologic features of Severely Obese Adults with Obstructive Sleep Apnea.
Article in International dental journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Three-dimensional upper airway phenotyping and OSA severity: a CT-based study.European radiology · 2026Article
- Effects of Volumetric Alterations of the Tongue Base on Craniofacial Growth in the Adult Minipig.Journal of morphology · 2026Article
- Childhood Obesity and Craniofacial Growth: A Cross-Sectional Orthodontic Cephalometric Study.Medicina (Kaunas, Lithuania) · 2026Article
- An Exploration of Craniofacial Features in Obstructive Sleep Apnea Using the Explainable Deep Learning Approaches.Nature and science of sleep · 2026Article
- Body Roundness Index Versus Body Mass Index: Differential Associations With Obstructive Sleep Apnea Syndrome and All-Cause Mortality in US Adults Aged 20 Years and Older.Brain and behavior · 2025Article
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Authors and funding
6 authors.
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Abstract
INTRODUCTION AND
aimsCraniofacial and upper airway development are closely associated with obstructive sleep apnea (OSA). This study aimed to analyse craniofacial and upper airway characteristics in adults with severe obesity and OSA to better understand the disease.
methodsNinety-four severely obese patients (BMI ≥ 35) underwent polysomnography (PSG) and lateral cephalograms to assess craniofacial and upper airway morphology. Cephalometric and airway measurements were analysed combined with PSG findings to evaluate craniofacial and airway features in severe OSA patients.
resultsThe study included 50 males and 44 females, with a mean age of 33.05 years and an average apnea-hypopnea index (AHI) of 52.22 events/h. Males had significantly higher AHI, neck circumference (NC), waist circumference, and arousal index, along with lower average and minimal oxygen saturation levels compared to females. Cephalometric analysis showed that males had greater mandibular ramus length and Sella-to-condyle vertical distance. Cross-correlation analysis indicated significant associations between AHI and both NC and the mandibular plane to Sella-Nasion line measurement. The Frankfurt horizontal plane to Nasion-Pogonion plane was correlated with BMI, NC, and waist circumference. Hyoid bone position was linked to tongue volume, Y-axis angle, pharyngeal airway space, facial height, and lip length. Tongue volume correlated with mandibular ramus length, upper anterior tooth angle, and upper lip length. Snoring index was associated with pharyngeal airway space and tongue height, while pharyngeal airway space width was related to oxygen saturation levels.
conclusionSevere obese individuals, particularly males, experience more severe OSA symptoms. A complex interplay exists between OSA, craniofacial morphology, and airway structure. CLINICAL RELEVANCE: Craniofacial and dental features are consistent in severe obese OSA patients, suggesting that obesity-related fat accumulation has a greater impact on respiratory function than skeletal structure or dental alignment.
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