Evidence map›Paper›PMID 40184513›Full record

ArticleAdvances in skin & wound care2025

Massive Malignant Transformation in a Patient with Hidradenitis Suppurativa during Anti-Tumor Necrosis Factor Treatment.

Gabija Rudzikaitė, Jorinta Jokubaitė, Dominykas Markevičius, Justinas Pamedys, Tadas Raudonis

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Advances in skin & wound care, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gabija RudzikaitėIn the Clinic of Infectious Diseases and Dermatovenereology, Faculty of Medicine, Vilnius University, Vilnius, Lithuania, Gabija Rudzikaitė, MD, is Dermatovenereologist; Jorinta Jokubaitė, MD, is Resident Doctor in Dermatovenereology; and Dominykas Markevičius, MD, is Resident Doctor in Plastic and Reconstructive Surgery. Justinas Pamedys, MD, is Surgical Pathologist, National Centre of Pathology Affiliated to Vilnius University Hospital Santaros Klinikos, Vilnius. Tadas Raudonis, MD, is Head, Centre of Dermatovenereology, Clinic of Infectious Diseases and Dermatovenereology, Faculty of Medicine, Vilnius University.ORCID 0009-0001-3478-7994
Jorinta Jokubaitė
Dominykas Markevičius
Justinas Pamedys
Tadas Raudonis

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

abstractHidradenitis suppurativa (HS) is a chronic skin condition that can lead to significant morbidity and, in some cases, transformation to squamous cell carcinoma (SCC). This report details the case of a 53-year-old man with a history of HS treatment with adalimumab and systemic antibiotics who developed well-differentiated SCC. For this malignant transformation, the patient required aggressive management, including radiation therapy, wide excision, and reconstructive surgery. Follow-up showed no disease progression. This case highlights the importance of early detection, routine screening, and a multidisciplinary approach in managing the risk of SCC in patients with HS.

Indexed as

AdalimumabCarcinoma, Squamous CellCell Transformation, NeoplasticHidradenitis SuppurativaSkin NeoplasmsTumor Necrosis Factor-alphaHumansMaleMiddle AgedAdalimumabTumor Necrosis Factor-alphaadalimumabhidradenitis suppurativamalignancysquamous cell carcinoma

Identifiers

PMID40184513
PMCPMC12244957

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.