Evidence map›Paper›PMID 40184237›Full record

Observational studyAddiction biology2025

Effects of Cigarette Smoking and 3-Day Smoking Abstinence on Translocator Protein 18 kDa Availability: A [

Arthur L Brody, Andre Y Sanavi, Renee Beverly-Aylwin, Natalie Guggino, Anna K Mischel, Alvin Wong, Ji Hye Bahn, Mark G Myers, Brinda Rana, David Vera and 4 more

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Addiction biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Arthur L BrodyDepartment of Psychiatry, University of California San Diego, San Diego, California, USA.ORCID 0000-0003-2614-8495
Andre Y SanaviDepartment of Psychiatry, University of California San Diego, San Diego, California, USA.
Renee Beverly-AylwinDepartment of Psychiatry, University of California San Diego, San Diego, California, USA.
Natalie GugginoDepartment of Psychiatry, University of California San Diego, San Diego, California, USA.
Anna K MischelDepartment of Psychiatry, University of California San Diego, San Diego, California, USA.
Alvin WongDepartment of Psychiatry, University of California San Diego, San Diego, California, USA.
Ji Hye BahnDepartment of Psychiatry, University of California San Diego, San Diego, California, USA.
Mark G MyersDepartment of Psychiatry, University of California San Diego, San Diego, California, USA.
Brinda RanaDepartment of Psychiatry, University of California San Diego, San Diego, California, USA.
David VeraDepartment of Radiology, University of California San Diego, San Diego, California, USA.
Kishore K KottaDepartment of Radiology, University of California San Diego, San Diego, California, USA.
Jeffrey H MeyerAzrieli Centre for Neuro-Radiochemistry, Brain Health Imaging Centre, Campbell Family Mental Health Research Institute, CAMH, Toronto, Canada.
Jared W YoungDepartment of Psychiatry, University of California San Diego, San Diego, California, USA.
Carl K HohDepartment of Radiology, University of California San Diego, San Diego, California, USA.

Funding

Cross-species studies of smoking effects on cognition and neuroinflammation in HIVR01DA044909 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BRODY, ARTHUR, YOUNG, JARED WILLIAM · 2017 to 2021
$4.3M
NIDA NIH HHS R01 DA044909NIDA NIH HHS R01DA44909Tobacco-Related Disease Research Program 28IR-0064
6 · The paper itself

Abstract

With the many negative health consequences of cigarette smoking, quitting is known to improve health in multiple domains. Using positron emission tomography/computed tomography (PET/CT) scanning, our group previously demonstrated that smokers have lower levels than nonsmokers of translocator protein binding both acutely and following overnight abstinence. Here, we sought to determine the effects of longer smoking abstinence on this marker of gliosis for microglia and astroglia, as well as explore associations between the marker and smoking-related symptoms. This observational study was performed in an academic VA medical centre. Fifty-nine generally healthy Veterans who were either nonsmokers (n = 15) or smokers (n = 44) participated in the study. Participants completed an intake visit to evaluate for inclusion/exclusion criteria, [

Indexed as

BrainCigarette SmokingReceptors, GABASmoking CessationAdultAnilidesFemaleGliosisHumansMagnetic Resonance ImagingMaleMiddle AgedPositron-Emission TomographyPositron Emission Tomography Computed TomographyPyridinesVeteransAnilidesN-(2-((N-(4-phenoxypyridin-3-yl)acetamido)methyl)phenoxy)ethyl fluoridePyridinesReceptors, GABATSPO protein, humanNeuroinflammationPositron Emission TomographyTobacco Dependence

Identifiers

PMID40184237
PMCPMC11970430

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.