Evidence map›Paper›PMID 40184176›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

Disease resistance is more costly at younger ages: An explanation for the maintenance of juvenile susceptibility in a wild plant.

Samuel P Slowinski, Allyson K Kido, Laura W Alexander, Andrea H Shirdon, Emily L Bruns

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Disease resistance is more costly at younger ages: An explanation for the maintenance of juvenile susceptibility in a wild plant.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Samuel P SlowinskiDepartment of Biology, University of Maryland, College Park, MD 20784.ORCID 0000-0002-2827-9387
Allyson K KidoDepartment of Biology, University of Maryland, College Park, MD 20784.
Laura W AlexanderDepartment of Integrative Biology, University of California at Berkeley, Berkeley, CA 94720.
Andrea H ShirdonDepartment of Biology, University of Maryland, College Park, MD 20784.
Emily L BrunsDepartment of Biology, University of Maryland, College Park, MD 20784.ORCID 0000-0003-4184-0922

Funding

National Science Foundation (NSF) 1936334
6 · The paper itself

Abstract

High juvenile susceptibility drives infectious disease epidemics across kingdoms, yet the evolutionary mechanisms that maintain this susceptibility are unclear. We tested the hypothesis that juvenile susceptibility is maintained by high costs of resistance by quantifying the genetic correlation between host fitness and age-specific innate resistance to a fungal pathogen in a wild plant. We separately measured the resistance of 45 genetic families of the wild plant,

Indexed as

BasidiomycotaDisease ResistancePlant DiseasesSileneBiological EvolutionDisease SusceptibilityHost-Pathogen Interactionsage-specific resistancedisease persistencedisease resistancetrade-offs

Identifiers

PMID40184176
PMCPMC12002266

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.