Evidence map›Paper›PMID 40184153›Full record

ArticleCirculation. Cardiovascular quality and outcomes2025

Comparing Cardiovascular Mortality Estimates From Global Burden of Disease and From the Centers for Disease Control and Prevention Wide-Ranging Online Data for Epidemiological Research.

Abdul Mannan Khan Minhas, Sadeer Al-Kindi, Harriette G C Van Spall, Dmitry Abramov

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Circulation. Cardiovascular quality and outcomes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Abdul Mannan Khan MinhasSection of Cardiovascular Research, Department of Medicine, Baylor College of Medicine Houston, TX (A.M.K.M.).ORCID 0000-0002-9829-3520
Sadeer Al-KindiDivision of Cardiology, Houston Methodist, Houston, TX (S.A.-K.).ORCID 0000-0002-1122-7695
Harriette G C Van SpallDepartment of Medicine, McMaster University, and Population Health Research Institute, Hamilton, Canada (H.G.C.V.S.).ORCID 0000-0002-8370-4569
Dmitry AbramovDivision of Cardiovascular Medicine, Loma Linda University Medical Center, CA (D.A.).ORCID 0000-0003-0571-3109

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSeveral sources of data, including the Centers for Disease Control and Prevention Wide-Ranging Online Data for Epidemiological Research (CDC WONDER) and the Global Burden of Disease (GBD) data set, report causes of mortality in the United States. While CDC WONDER contains data based on death certificate codes, the GBD mortality data undergo additional processing, such as cause-of-death reassignment before reporting. Potential differences in reported mortality from cardiovascular disease in the United States between these 2 data sources have not been characterized.

methodsUS nationwide cardiovascular cause-of-death data for each year between 2000 and 2019 were obtained from the GBD and the Multiple Cause-of-Death files using CDC WONDER in this longitudinal study. In addition to mortality from cardiovascular disease, mortality from key components of cardiovascular disease, including ischemic heart disease, stroke, and atrial fibrillation/flutter, was determined from each data set. Absolute and crude mortality rates per 100 000 are reported for each data set. Percent differences in cardiovascular mortality from GBD and CDC WONDER and percent changes in cardiovascular mortality across years were calculated.

resultsIn 2019, GBD reported 957 455 (95% uncertainty interval, 855 065-1 013 175) cardiovascular deaths, while CDC WONDER reported 859 290 cardiovascular deaths in the United States. Between 2000 and 2019, the reported crude mortality rates from cardiovascular causes in GBD decreased from 327 (297-341) to 292 (261-309), a reduction of 10.7%, and decreased in CDC WONDER from 335 (334-335) to 267 (266-267), a reduction of 20.3%. In 2019, the reported mortality rates for components of cardiovascular disease were higher in GBD compared with CDC WONDER for ischemic heart disease (percent difference, 54.5%), stroke (percent difference, 26.1%), and atrial fibrillation/flutter (percent difference, 25.0%).

conclusionsThere are prominent differences in reported cardiovascular mortality between GBD and CDC WONDER data.

Indexed as

Cardiovascular DiseasesCenters for Disease Control and Prevention, U.S.Databases, FactualGlobal Burden of DiseaseAgedCause of DeathFemaleHumansLongitudinal StudiesMaleMiddle AgedRisk AssessmentTime FactorsUnited Statescardiovascular diseasescause of deathdeath certificatesstroke

Identifiers

PMID40184153

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.