Evidence map›Paper›PMID 40184151›Full record

ArticleCirculation. Cardiovascular quality and outcomes2025

Incidence, Prevalence, and Trends in Mortality and Stroke Among Medicare Beneficiaries With Atrial Fibrillation: 2013 to 2019.

Nichole M Rogovoy, Stephen Kearing, Weiping Zhou, James V Freeman, Jonathan P Piccini, Sana M Al-Khatib, Emily P Zeitler

Abstract read
In one paragraph

Article in Circulation. Cardiovascular quality and outcomes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Nichole M RogovoyDepartment of Medicine & Heart and Vascular Center, Division of Cardiovascular Medicine, Dartmouth-Hitchcock Medical Center, Dartmouth Health, Lebanon NH (N.M.R., S.K., W.Z., E.P.Z.).
Stephen KearingDepartment of Medicine & Heart and Vascular Center, Division of Cardiovascular Medicine, Dartmouth-Hitchcock Medical Center, Dartmouth Health, Lebanon NH (N.M.R., S.K., W.Z., E.P.Z.).
Weiping ZhouDepartment of Medicine & Heart and Vascular Center, Division of Cardiovascular Medicine, Dartmouth-Hitchcock Medical Center, Dartmouth Health, Lebanon NH (N.M.R., S.K., W.Z., E.P.Z.).
James V FreemanDepartment of Medicine, Yale School of Medicine, New Haven, CT (J.V.F.).ORCID 0000-0002-4614-6879
Jonathan P PicciniDepartment of Medicine, Duke University Medical Center and Duke Clinical Research Institute, Durham, NC (J.P.P., S.M.A.-K.).ORCID 0000-0003-0772-2404
Sana M Al-KhatibDepartment of Medicine, Duke University Medical Center and Duke Clinical Research Institute, Durham, NC (J.P.P., S.M.A.-K.).ORCID 0000-0002-3561-0146
Emily P ZeitlerDepartment of Medicine & Heart and Vascular Center, Division of Cardiovascular Medicine, Dartmouth-Hitchcock Medical Center, Dartmouth Health, Lebanon NH (N.M.R., S.K., W.Z., E.P.Z.).ORCID 0000-0002-4848-4775

Funding

Understanding the Influence of Community-level Deprivation and Rural Residence in Cancer CareP20GM148278 · NIGMS · DARTMOUTH-HITCHCOCK CLINIC · PI MARK A CREAGER · 2023 to 2026
$11.6M
Neurocognition and Greater Maintenance of Sinus Rhythm in AF (NOGGIN AF)R01AG074185 · NIA · DUKE UNIVERSITY · PI MATHEW, JOSEPH P, PICCINI, JONATHAN PAUL · 2021 to 2025
$3.7M
NIA NIH HHS R01 AG074185NIGMS NIH HHS P20 GM148278
6 · The paper itself

Abstract

backgroundAtrial fibrillation (AF) is known to be associated with increased risks of stroke and death, but contemporary studies of this association are lacking. We evaluated trends in stroke and death among Medicare beneficiaries with AF between 2013 and 2019.

methodsMedicare fee-for-service beneficiaries >65 years old (2011-2019) were included. AF incidence and prevalence were calculated overall and by age group, sex, race, and rurality. Within incident cohorts, the 1-year stroke rate was assessed. Age- and sex-adjusted mortality at 30 days, 1 year, and 3 years was calculated in each incident cohort.

resultsThe mean number of Medicare beneficiaries with incident AF per year was 572 630 from 2013 to 2019 (30.44 per 1000 patient-years). The study cohort on average was 79±7.7 years old, 52% female, 88% white, and 83% urban dwelling. Incidence and prevalence of AF increased with age and was highest among White beneficiaries; the incidence was greater in male compared with female beneficiaries. Differences by rurality were not seen. Overall AF prevalence per 1000 beneficiaries increased minimally but steadily from 2013 to 2019 reflecting an increase among male (104-109 per 1000) but not female beneficiaries (82.5 per 1000). The 1-year rate of stroke after incident AF peaked in the 2015 cohort (50.5 per 1000); the rate was at its lowest among the 2018 cohort (41.89 per 1000). Incident AF was associated with mortality that was 3.2× greater than expected at 1 year, but overall mortality and the magnitude of the AF-related mortality risk decreased steadily over time from 22% to 20%.

conclusionsFrom 2013 to 2019, AF incidence and prevalence among Medicare beneficiaries were relatively stable but have varied by important demographic subgroups with age and sex remaining powerful risk factors. In contrast, mortality and stroke after incident AF have decreased significantly throughout this era.

Indexed as

Atrial FibrillationMedicareStrokeAgedAged, 80 and overAge DistributionAge FactorsFee-for-Service PlansFemaleHumansIncidenceMalePrevalencePrognosisRetrospective StudiesRisk Assessmentatrial fibrillationMedicaremortalityrisk factorsstroke

Identifiers

PMID40184151
PMCPMC12092179

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.