Trial reportMedicine2025
The effect of Chinese 5-element music with midnight-noon ebb-flow theory on depression, anxiety, quality of life satisfaction among older adults: A randomized controlled trial.
Trial report in Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effectiveness of group-based art interventions for late-life depression: a systematic review and meta-analysis of randomized controlled trials.BMC medicine · 2026Pooled it
- [Sub-committee of Anesthesiology of Guangzhou Integrated Traditional Chinese and Western Medicine Society].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2025Article
- Article
- Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe prevalence rates of depression and anxiety are constantly increasing, and the aging population is growing in China. Music-based intervention is a nonpharmacological treatment that is used to treat depression and anxiety and that has very few side effects. The aim of this study was to explore the effect of Chinese 5-element music-based intervention (CFEMBI) based on the midnight-noon ebb-flow theory on depression and anxiety among older adults.
methodsA total of 86 patients were divided into the control and experimental groups. The control group underwent a traditional CFEMBI, and the experimental group underwent a CFEMBI based on the midnight-noon ebb-flow theory. Outcomes were assessed at the 4th week, 8th week, and 12th week during the intervention.
resultsAfter the 12th week, there was a significant difference in scores on the Hamilton Depression Rating Scale (HAM-D) between the control and experimental groups (Z = -6.375, P value < 0.001). Additionally, there was a significant difference in the cure rate of depression between the 2 groups at week 12 (P < .001). After the 8th week, there was a significant difference in Hamilton Anxiety Rating Scale (HAM-A) scores between the 2 groups (t = 7.422, P value < 0.001). Furthermore, there was a significant difference in scores on the Quality of Life, Enjoyment, and Satisfaction Questionnaire-Short Form (Q-LES-Q-SF) between the 2 groups (Z = 4.991, P value < 0.001; Z = 3.023, P value < 0.01; Z = 3.023, P value < 0.01).
conclusionsCFEMBI based on the midnight-noon ebb-flow theory is effective at alleviating depression and anxiety in older adults and improving life satisfaction.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.