Evidence map›Paper›PMID 40184092›Full record

Observational studyMedicine2025

Recovery from inferior alveolar neurosensory changes after lower third molar extraction: A multicenter, retrospective study.

Tomofumi Naruse, Koki Suyama, Hiromasa Fukushima, Norio Nakamura, Kentaro Yamashita, Kohei Furukawa, Kota Morishita, Satoshi Rokutanda, Tomohiro Yamada

Abstract readMulticenter StudyObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tomofumi NaruseDepartment of Oral and Maxillofacial Surgery, Graduate School of Biomedical Sciences, Nagasaki University, 1-7-1 Sakamoto, Nagasaki, Japan.ORCID 0009-0003-1966-1968
Koki SuyamaDepartment of Oral and Maxillofacial Surgery, Graduate School of Biomedical Sciences, Nagasaki University, 1-7-1 Sakamoto, Nagasaki, Japan.
Hiromasa FukushimaDepartment of Oral and Maxillofacial Surgery, Graduate School of Biomedical Sciences, Nagasaki University, 1-7-1 Sakamoto, Nagasaki, Japan.
Norio NakamuraDepartment of Dentistry and Oral Surgery, Juko Memorial Nagasaki Hospital, 6-17, Maruo, Nagasaki, Japan.
Kentaro YamashitaDepartment of Dentistry and Oral Surgery, Juko Memorial Nagasaki Hospital, 6-17, Maruo, Nagasaki, Japan.
Kohei FurukawaDepartment of Oral and Maxillofacial Surgery, Graduate School of Biomedical Sciences, Nagasaki University, 1-7-1 Sakamoto, Nagasaki, Japan.
Kota MorishitaDepartment of Oral and Maxillofacial Surgery, Graduate School of Biomedical Sciences, Nagasaki University, 1-7-1 Sakamoto, Nagasaki, Japan.
Satoshi RokutandaDepartment of Dentistry and Oral Surgery, Juko Memorial Nagasaki Hospital, 6-17, Maruo, Nagasaki, Japan.
Tomohiro YamadaDepartment of Oral and Maxillofacial Surgery, Graduate School of Biomedical Sciences, Nagasaki University, 1-7-1 Sakamoto, Nagasaki, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inferior alveolar (IA) neurosensory changes are complications that infrequently occur after third molar extraction. However, no adequate treatment has been established for IA neurosensory changes. The present study aimed to establish an effective treatment for IA neurosensory changes following lower third molar extraction. A total of 10,062 patients (12,776 teeth) who underwent lower third molar extractions were enrolled between April 2014 and June 2022. The medical records of the patients were reviewed, and relevant data were extracted. The prevalence of risk factors for recovery from IA neurosensory changes was analyzed. In total, 221 patients (224 teeth) developed IA neurosensory changes. Temporary and permanent IA neurosensory changes occurred in 1.75% and 0.71% of patients, respectively. The 1-, 3-, and 6-month cumulative recovery rates were 25.0%, 60.1%, and 71.1%, respectively. Univariate analysis revealed that age < 40 years (hazard ratio [HR], 2.02; P < .001), local anesthesia (HR, 1.45; P = .03), and postoperative administration of corticosteroids (HR, 1.63; P = .04) were significantly associated with high recovery rates. The cumulative recovery rate significantly improved with corticosteroid administration (P = .04). However, no significant differences were observed using the propensity score matching method. No significant differences were observed with or without vitamin B12 administration. These results suggest that postoperative administration of corticosteroids enables recovery from IA neurosensory changes after third molar extraction.

Indexed as

Mandibular NerveMolar, ThirdPostoperative ComplicationsTooth ExtractionAdolescentAdrenal Cortex HormonesAdultFemaleHumansMaleMiddle AgedRetrospective StudiesRisk FactorsYoung AdultAdrenal Cortex Hormones

Identifiers

PMID40184092
PMCPMC11709186

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.