Evidence map›Paper›PMID 40183995›Full record

ReviewCurrent pain and headache reports2025

Neuropathic Pain: A Comprehensive Bibliometric Analysis of Research Trends, Contributions, and Future Directions.

Matteo Luigi Giuseppe Leoni, Marco Mercieri, Omar Viswanath, Marco Cascella, Martina Rekatsina, Alberto Pasqualucci, Annalisa Caruso, Giustino Varrassi

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Current pain and headache reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Matteo Luigi Giuseppe LeoniDepartment of Medical and Surgical Sciences and Translational Medicine, Sapienza University of Rome, Rome, Italy. matteolg.leoni@gmail.com.ORCID http://orcid.org/0000-0001-5228-3733
Marco MercieriDepartment of Medical and Surgical Sciences and Translational Medicine, Sapienza University of Rome, Rome, Italy.
Omar ViswanathDepartment of Anesthesiology, Creighton University School of Medicine, Phoenix, AZ, USA.
Marco CascellaDepartment of Medicine, Surgery and Dentistry, University of Salerno, Baronissi, Italy.
Martina RekatsinaDepartment of Anaesthesia and Pain Management, National and Kapodistrian University of Athens, Athens, Greece.
Alberto PasqualucciAnaesthesiology and Critical Care, University of Perugia, Perugia, Italy.
Annalisa CarusoDepartment of Surgery, ASST Lodi, Lodi, Italy.
Giustino VarrassiFondazione Paolo Procacci, 00193, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNeuropathic pain represents a significant public health concern due to its complex pathophysiology and the disability it can cause. Despite advancements in understanding its underlying mechanisms and potential treatments, challenges persist in achieving effective management. This bibliometric analysis aims to offer a comprehensive overview of research trends, key contributors, and existing gaps in the literature on neuropathic pain, providing valuable insights to guide future studies and enhance clinical approaches.

methodsA bibliometric analysis was conducted using the Web of Science Core Collection (WoSCC) database. Key metrics, including publication trends, citation patterns, co-authorship networks, and keyword co-occurrence, were evaluated. Statistical analyses included average annual percentage change (APC) assessments and trend forecasting with an Auto Regressive Integrated Moving Average (ARIMA) model.

resultsA total of 9,974 studies published between 2005 and 2024 were included. Publications peaked between 2021 and 2022 but showed a slight decline thereafter, with forecasts predicting a steady increase from 2025 to 2030. Most papers were published in high-impact Q1 journals, reflecting the quality of research. Co-authorship analysis revealed central hubs of collaboration in the USA and China, with limited integration of smaller countries into the global research network. Keyword analysis identified multiple thematic clusters, including "chronic pain," "molecular mechanisms," and "clinical management." Specific gaps were noted in understanding personalized therapeutic approaches, and non-pharmacological interventions.

conclusionsThis analysis underscores the critical need for continued research to address gaps in diagnosis, treatment, and management of neuropathic pain. Strengthening international collaborations and fostering multidisciplinary efforts will be pivotal in advancing this field.

Indexed as

BibliometricsBiomedical ResearchNeuralgiaHumansBibliometric analysisChronic painNeuropathic painNeurostimulationPain managementPain researchResearch trends

Identifiers

PMID40183995
PMCPMC11971142

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.