Evidence map›Paper›PMID 40183988›Full record

Trial reportSleep & breathing = Schlaf & Atmung2025

Patterns of adherence to continuous positive airway pressure and mandibular advancement splints in pregnant individuals with sleep-disordered breathing.

Joshua Smocot, Nelly Huynh, Pattaraporn Panyarath, R John Kimoff, Sara Meltzer, Léa Drouin-Gagné, Raphieal Newbold, Courtney Hebert, Andrea Benedetti, Jean-Patrick Arcache and 4 more

3 registry-linked trialsAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Sleep & breathing = Schlaf & Atmung, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02245659 nacompletednot on this map

The Effect of Continuous Positive Airway Pressure (CPAP) Treatment on Glycemic Control in Gestational Diabetes: A Pilot Randomized-Controlled Trial

TypeinterventionalSponsorMcGill University Health Centre/Research Institute of the McGill University Health CentreRan2015 to 2018Enrolled46ConditionsPregnancy, Sleep-disordered Breathing, Gestational DiabetesArmsCPAP, Nasal dilator strip
NCT03138291 nacompletednot on this map

Efficacy of Oral Appliances on Obstructive Sleep Apnea During Pregnancy

TypeinterventionalSponsorUniversité de MontréalRan2016 to 2023Enrolled17ConditionsSleep Apnea, Obstructive, Pregnancy RelatedArmsSomnodent
NCT03309826 nacompletednot on this map

Effects of Positive Airway Pressure Treatment of Obstructive Sleep-disordered Breathing on Maternal and Fetal Outcomes in Hypertensive Disorders of Pregnancy: a Pilot Randomized Controlled Trial

TypeinterventionalSponsorDr John KimoffRan2017 to 2021Enrolled48ConditionsHypertensive Disorder of Pregnancy, Sleep Apnea, ObstructiveArmsPositive Airway Pressure, Nasal Dilator Strip
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Joshua SmocotResearch Institute of the McGill University Health Centre, McGill University, Montreal, QC, Canada.
Nelly HuynhFaculté de Médecine Dentaire, Université de Montréal, Montréal, Québec, Canada.
Pattaraporn PanyarathResearch Institute of the McGill University Health Centre, McGill University, Montreal, QC, Canada.
R John KimoffResearch Institute of the McGill University Health Centre, McGill University, Montreal, QC, Canada.
Sara MeltzerDivision of Endocrinology, Department of Medicine, McGill University, Montreal, Québec, Canada.
Léa Drouin-GagnéFaculté de Médecine Dentaire, Université de Montréal, Montréal, Québec, Canada.
Raphieal NewboldResearch Institute of the McGill University Health Centre, McGill University, Montreal, QC, Canada.
Courtney HebertResearch Institute of the McGill University Health Centre, McGill University, Montreal, QC, Canada.
Andrea BenedettiResearch Institute of the McGill University Health Centre, McGill University, Montreal, QC, Canada.
Jean-Patrick ArcacheFaculté de Médecine Dentaire, Université de Montréal, Montréal, Québec, Canada.
Anne-Maude MorencyResearch Institute of the McGill University Health Centre, McGill University, Montreal, QC, Canada.
Natasha GarfieldDivision of Endocrinology, Department of Medicine, McGill University, Montreal, Québec, Canada.
Evelyne ReyFaculté de Médecine, Université de Montréal, CHU Sainte-Justine, Montréal, Québec, Canada.
Sushmita PamidiResearch Institute of the McGill University Health Centre, McGill University, Montreal, QC, Canada. sushmita.pamidi@mcgill.ca.ORCID 0000-0001-6848-8901

Funding

CIHR MOP-136886Fonds de Recherche du Québec - Santé Junior 1
6 · The paper itself

Abstract

purposeNight-to-night adherence to sleep-disordered breathing (SDB) treatment with either continuous positive airway pressure (CPAP) or mandibular advancement splints (MAS) in pregnancy has not been well characterized. The objective of this study was to assess night-to-night adherence patterns from existing CPAP and MAS data in pregnancy.

methodsThree separate pregnancy cohorts evaluating treatment for SDB in the second and third trimester were used: 1) CPAP in gestational diabetes mellitus (GDM), 2) CPAP in hypertensive disorders of pregnancy (HDP), and 3) mandibular advancement splints (MAS). The first 30 days of objective adherence data obtained from CPAP and MAS devices were used in this descriptive analysis.

resultsData from 37 CPAP users and 15 MAS users was analyzed. For the GDM and HDP cohorts, three patterns of adherence were observed: 1) consistent CPAP users (38%), 2) improved CPAP usage after initial adaptation (16%), and 3) inconsistent CPAP users (46%). For the MAS cohort, the three observed patterns of adherence were: 1) consistent MAS users (47%), 2) initial usage with subsequent decrease in adherence (20%), and 3) inconsistent MAS users (33%). Participant characteristics (demographics, disease severity) were similar between adherence groups, with the exception of longer total sleep time in consistent CPAP users of the GDM cohort and greater gestational age in consistent CPAP users of the HDP cohort.

conclusionOverall, objective night-to-night adherence patterns revealed that almost half of CPAP and MAS users had difficulty adapting to treatment in the first 30 days of treatment. Early usage patterns in pregnancy may provide insight into identifying patients who are at risk for poor adherence and for developing tailored and timely interventions to enhance adherence to therapy.

trial registrationClinicalTrials.gov Identifiers: NCT02245659, NCT03309826, NCT03138291.

Indexed as

Continuous Positive Airway PressureMandibular AdvancementPatient CompliancePregnancy ComplicationsSleep Apnea, ObstructiveAdultCohort StudiesDiabetes, GestationalFemaleHumansPregnancyContinuous positive airway pressureMandibular advancement splintNight-to-night adherenceOral appliancePregnancySleep apneaSleep-disordered breathing

Identifiers

PMID40183988

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.