ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2025
The effects of nutritional habits and physical activity on treatment response and survival in patients with lung cancer.
Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Physical activity trajectories and associated factors in patients with lung cancer undergoing chemotherapy: A longitudinal study.Asia-Pacific journal of oncology nursing · 2026Article
- Exploring Physical Activity Levels, Barriers, and Education Sources in People with Cancer Undergoing Chemotherapy.Cancers · 2025Article
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3 authors.
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Abstract
backgroundLung cancer is a malignancy marked by low treatment response rates and poor survival outcomes, despite significant advancements in diagnostic and therapeutic approaches. This study aims to examine the impact of dietary habits and physical activity levels on chemotherapy response and survival in patients diagnosed with advanced-stage non-small cell lung cancer.
methodsPatients diagnosed with stage IV non-small cell lung cancer and scheduled to receive platinum-based chemotherapy as the initial treatment were included in the study. Sociodemographic and cancer-related characteristics were documented. At the beginning of treatment, the patients' dietary habits and physical activity levels were evaluated using the "Mediterranean Diet Adherence Scale," the "International Physical Activity Questionnaire," and the "Food Consumption Frequency Form," while their average daily step count was calculated. The study investigated the relationships between dietary habits and physical activity levels with treatment response, 6-month survival, progression-free survival, and chemotherapy-related side effects.
resultsThe study included a total of 37 patients, 35 of whom were male, with a mean age of 63.49 years. The 6-month survival rate among these patients was 81.1%. In terms of treatment response, 35.1% of patients experienced disease progression, 54.1% demonstrated partial regression, and 8.1% achieved complete regression. Notably, the 6-month survival rate was significantly higher in minimally physically active patients compared to inactive patients (p = 0.022). Furthermore, patients adhering to the Mediterranean diet exhibited a significantly higher 6-month survival rate compared to those who did not follow the diet (p = 0.019). High adherence to the Mediterranean diet was also associated with a significantly lower incidence of chemotherapy-related gastrointestinal side effects (p < 0.001).
conclusionThis study demonstrated that physical activity and adherence to the Mediterranean diet positively impact 6-month survival and reduce the incidence of chemotherapy-related side effects.
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