Evidence map›Paper›PMID 40183970›Full record

ArticleDiscover oncology2025

Constructing a prognostic model based on MPT-related genes and investigate the characteristics of immune infiltration in bladder cancer.

Lei Yang, Zhiqiang Zhang, Mengfan Xu, Muhan Shang, Haibing Wang, Zhiqi Liu

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PubMed Full text at PMC Publisher
In one paragraph

Article in Discover oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lei YangDepartment of Urology, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, Anhui Province, China.
Zhiqiang ZhangDepartment of Urology, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, Anhui Province, China. zhangzq_urology@126.com.
Mengfan XuDepartment of Urology, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, Anhui Province, China.
Muhan ShangDepartment of Urology, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, Anhui Province, China.
Haibing WangDepartment of Urology, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, Anhui Province, China.
Zhiqi LiuDepartment of Urology, The Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, Anhui Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeExploring the expression of Mitochondrial Permeability Transition Dependent Necrosis lncRNA in bladder cancer and elucidate their precise function within the tumor microenvironment and impact on prognosis.

methodsWe employed a comprehensive bioinformatics approach to investigate the function and influence of lncRNA in bladder cancer. Gene expression data, clinical data, and mutation data of bladder cancer are obtained from TCGA database.

resultsWe developed a new prognostic model incorporating 6 lncRNAs. The predictive efficacy of this model for bladder cancer prognosis was validated. Furthermore, we investigated the influence of model on the tumor microenvironment and drug sensitivity.

conclusionThis study presents a novel prognostic framework for bladder cancer that holds great potential for enhancing prognostic prediction accuracy and optimizing treatment strategies for patients with this disease.

Indexed as

ApoptosisBladder cancerDrug sensitiveImmune infiltrationMPT

Identifiers

PMID40183970
PMCPMC11971081

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.