Observational studyInternational urology and nephrology2025
Health literacy, illness perception, and their association with medication adherence in end-stage renal disease.
Observational study in International urology and nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Medication adherence tools and measures in chronic kidney disease: a systematic review.BMC nephrology · 2026Pooled it
- Illness perception and its relationship with nursing care behaviors in hemodialysis patients: A cross-sectional descriptive study.Medicine · 2026Article
- Knowledge, attitudes, and practices of pharmacists towards chronic kidney disease in Rawalpindi and Islamabad, Pakistan: a cross-sectional study.BMC medical education · 2026Article
- Illness perception mediates the association between emotional intelligence and symptom distress among patients undergoing peritoneal dialysis: a Common-Sense Model approach.Frontiers in public health · 2026Article
- The Association Between Ischemic Stroke Patients' Illness Perception and Adherence to Rehabilitation Exercises: An Analysis of a Moderated Chain Mediation Model.Patient preference and adherence · 2025Article
- Self-perceptions of aging mediate the association between illness perception and influenza vaccine hesitancy in older adults with pneumonia during the 2024-2025 influenza season.Frontiers in public health · 2025Article
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Authors and funding
6 authors.
Funding
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Abstract
backgroundMedication non-adherence is a prevalent and complicated problem among patients receiving hemodialysis. Strictly following the prescribed medication regimen is crucial for achieving successful dialysis in end-stage renal disease.
objectiveThis study aimed to investigate how health literacy and illness perception influence medication adherence in hemodialysis patients.
methodsAn observational cross-sectional study was conducted from October 2023 to February 2024 at dialysis units of multisite hospitals across Rawalpindi and Islamabad, Pakistan. A pre-validated, reliable, and interview-based questionnaire was utilized, and a convenience sampling technique was employed to collect data from 390 patients. The Statistical Package for the Social Sciences version 23.0 was utilized for statistical analysis.
resultsMore than half of the dialysis patients were female, 52.8%, 31% were between the ages of 46-60, and 66.6% had minimal or no education. Of the patients studied, 45.1% exhibited inadequate health literacy, 46.7% held negative perceptions of their illness, and 41.8% demonstrated low levels of medication adherence. The study found a weak correlation: a negative correlation between health literacy and illness perception (r = - 0.080), a positive correlation between health literacy and medication adherence (r = 0.024), and a negative correlation between illness perception and medication adherence (r = -0.061), none of which were statistically significant.
conclusionA considerable proportion of the patients demonstrate low medication adherence, inadequate health literacy, and negative perceptions of their illness, highlighting the urgent need for targeted interventions. Structured educational programs, motivational interviewing, individual or group support, and in-person or remote (web- or telephone-based) counseling can help address these issues. Additionally, healthcare professionals-led interventions by doctors, pharmacists, and nurses play a crucial role in raising awareness, enhancing medication adherence, and optimizing treatment outcomes.
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