Evidence map›Paper›PMID 40183777›Full record

ArticleeLife2025

The rhizobial effector NopT targets Nod factor receptors to regulate symbiosis in

Hanbin Bao, Yanan Wang, Haoxing Li, Qiang Wang, Yutao Lei, Ying Ye, Syed F Wadood, Hui Zhu, Christian Staehelin, Gary Stacey and 2 more

Abstract read
In one paragraph

Article in eLife, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Hanbin Bao *National Key Lab of Agricultural Microbiology, Hubei Hongshan Laboratory, Huazhong Agricultural University, Wuhan, China.ORCID https://orcid.org/0000-0002-2950-1234
Yanan Wang *National Key Lab of Agricultural Microbiology, Hubei Hongshan Laboratory, Huazhong Agricultural University, Wuhan, China.ORCID https://orcid.org/0000-0001-5797-1113
Haoxing LiNational Key Lab of Agricultural Microbiology, Hubei Hongshan Laboratory, Huazhong Agricultural University, Wuhan, China.
Qiang WangNational Key Lab of Agricultural Microbiology, Hubei Hongshan Laboratory, Huazhong Agricultural University, Wuhan, China.
Yutao LeiNational Key Lab of Agricultural Microbiology, Hubei Hongshan Laboratory, Huazhong Agricultural University, Wuhan, China.
Ying YeNational Key Lab of Agricultural Microbiology, Hubei Hongshan Laboratory, Huazhong Agricultural University, Wuhan, China.
Syed F WadoodState Key Laboratory of Biocontrol and Guangdong Key Laboratory of Plant Resources, School of Life Sciences, Sun Yat-sen University, Guangzhou, China.
Hui ZhuNational Key Lab of Agricultural Microbiology, Hubei Hongshan Laboratory, Huazhong Agricultural University, Wuhan, China.ORCID https://orcid.org/0000-0002-7273-8448
Christian StaehelinState Key Laboratory of Biocontrol and Guangdong Key Laboratory of Plant Resources, School of Life Sciences, Sun Yat-sen University, Guangzhou, China.
Gary StaceyDivisions of Plant Science and Technology, Christopher S. Bond Life Sciences Center, University of Missouri, Columbia, United States.ORCID https://orcid.org/0000-0001-5914-2247
Shutong XuNational Key Lab of Agricultural Microbiology, Hubei Hongshan Laboratory, Huazhong Agricultural University, Wuhan, China.
Yangrong CaoNational Key Lab of Agricultural Microbiology, Hubei Hongshan Laboratory, Huazhong Agricultural University, Wuhan, China.ORCID https://orcid.org/0000-0002-2252-6551

Funding

Fundamental Research Funds for the Central Universities 2662021JC010Fundamental Research Funds for the Central Universities 2662022SKYJ002National Key R&D Program of China 2019YFA0904700National Natural Science Foundation of China 32090063National Science Foundation Plant Genome Research Program 2048410
6 · The paper itself

Abstract

It is well documented that type-III effectors are required by Gram-negative pathogens to directly target different host cellular pathways to promote bacterial infection. However, in the context of legume-rhizobium symbiosis, the role of rhizobial effectors in regulating plant symbiotic pathways remains largely unexplored. Here, we show that NopT, a YopT-type cysteine protease of

Indexed as

Bacterial ProteinsLotusPlant ProteinsSinorhizobium frediiSymbiosisNicotianaSignal TransductionBacterial ProteinsPlant Proteinslegume–rhizobium symbiosisLotus japonicusNod factor receptorsNopTplant biologyrhizobial effector

Identifiers

PMID40183777
PMCPMC11970910

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.