Evidence map›Paper›PMID 40183723›Full record

ArticleThe Journal of adolescent health : official publication of the Society for Adolescent Medicine2025

Adverse Childhood Experiences and Unmet Health Care Needs Due to Cost and the COVID-19 Pandemic: A Nationally Representative Analysis of U.S. Adolescents.

Rohan Khazanchi, Ryan C L Brewster, Destiny G Tolliver, Nia J Heard-Garris, Aditi Vasan, Tyler N A Winkelman, Scott E Hadland

Abstract read
In one paragraph

Article in The Journal of adolescent health : official publication of the Society for Adolescent Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Rohan KhazanchiHarvard Internal Medicine-Pediatrics Residency Program at Brigham and Women's Hospital, Boston Children's Hospital, Boston Medical Center, Boston, Massachusetts; FXB Center for Health and Human Rights, Harvard University, Boston, Massachusetts; Health, Homelessness, and Criminal Justice Lab, Hennepin Healthcare Research Institute, Minneapolis, Minnesota; Department of Pediatrics, Harvard Medical School, Boston, Massachusetts. Electronic address: rohan.khazanchi@childrens.havard.edu.
Ryan C L BrewsterDepartment of Pediatrics, Harvard Medical School, Boston, Massachusetts; Boston Combined Residency Program, Boston Children's Hospital and Boston Medical Center, Boston, Massachusetts.
Destiny G TolliverDepartment of Pediatrics, Boston Medical Center, Boston, Massachusetts; Department of Pediatrics, Boston University School of Medicine, Boston, Massachusetts.
Nia J Heard-GarrisDivision of Advanced General Pediatrics, Department of Pediatrics, Ann & Robert H. Lurie Children's Hospital, Chicago, Illinois; Mary Ann & J. Milburn Smith Child Health Research, Outreach, and Advocacy Center, Stanley Manne Children's Research Institute, Ann & Robert H. Lurie Children's Hospital, Chicago, Illinois; Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, Illinois; Institute for Policy Research, Northwestern University, Chicago, Illinois.
Aditi VasanDepartment of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania; PolicyLab, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Tyler N A WinkelmanHealth, Homelessness, and Criminal Justice Lab, Hennepin Healthcare Research Institute, Minneapolis, Minnesota; Division of General Internal Medicine, Department of Medicine, Hennepin Healthcare, Minneapolis, Minnesota.
Scott E HadlandDepartment of Pediatrics, Harvard Medical School, Boston, Massachusetts; Division of Adolescent and Young Adult Medicine, Mass General Hospital for Children, Boston, Massachusetts.

Funding

University of Minnesota Clinical and Translational Science Institute (UMN CTSI)UM1TR004405 · NCATS · UNIVERSITY OF MINNESOTA · PI Bruce R Blazar, Damien A Fair · 2023 to 2026
$30.8M
The Cascade of Care for Medicaid-Enrolled Youth with Opioid Use DisorderR01DA057566 · NIDA · MASSACHUSETTS GENERAL HOSPITAL · PI Scott Evan Hadland, Arthur R Williams · 2022 to 2026
$2.9M
Collaborative Care Office-Based Opioid Treatment for Adolescents and Young AdultsK23DA045085 · NIDA · MASSACHUSETTS GENERAL HOSPITAL · PI HADLAND, SCOTT EVAN · 2018 to 2022
$1.1M
K Administrative Supplement:ACHiP-ACEs and Cardiometabolic Health in Pediatrics: Using a Coping and Stress Reduction Intervention to Reduce Cardiometabolic Risk in Adolescents with AdversityK01HL147995 · NHLBI · LURIE CHILDREN'S HOSPITAL OF CHICAGO · PI HEARD-GARRIS, NIA JENEE' · 2019 to 2023
$886k
Substance Use and Firearm Injuries among Medicaid-enrolled YouthK18DA059913 · NIDA · MASSACHUSETTS GENERAL HOSPITAL · PI HADLAND, SCOTT EVAN · 2023 to 2023
$564k
AHRQ HHS K08 HS029396NCATS NIH HHS UM1 TR004405NHLBI NIH HHS K01 HL147995NIDA NIH HHS K18 DA059913NIDA NIH HHS K23 DA045085NIDA NIH HHS R01 DA057566
6 · The paper itself

Abstract

purposeAdverse childhood experience (ACE) exposure and poor mental health are closely intertwined. In 2020, the prevalence of both began precipitously increasing among adolescents. We explored associations of individual and cumulative ACE exposure with cost and COVID-19 pandemic-related unmet health needs to assess ACEs as risk markers for broader structural adversity.

methodsWe conducted a nationally representative analysis of 5,536 adolescents (weighted N = 20,294,070) aged 13-17 years using the 2019 and 2021 National Health Interview Survey. Outcomes included mental health symptoms, preventive care access, cost and COVID-19-related unmet needs, and health care use. We estimated associations with lifetime exposure to 4 ACEs using marginal effects from multivariable logistic regressions.

resultsMillions of adolescents were exposed to parental incarceration (7.8%, N = 1,407,670), neighborhood violence (6.9%, N = 1,567,483), a guardian with serious mental illness (10.3%, N = 2,088,957), and/or a guardian with alcohol or drug problems (11.4%, N = 2,304,953). Overall, 77.7% (N = 15,758,023), 13.2% (N = 2,671,342), and 9.2% (N = 1,864,704) were exposed to 0, 1, and 2+ of these ACEs. In adjusted models, compared with exposure to 0 ACEs, exposure to 1 or 2+ ACEs was positively associated with anxiety and depression symptom frequency, urgent care and emergency department use, trouble paying medical bills, delayed and forgone mental health care due to cost, and delayed and forgone care due to the COVID-19 pandemic. DISCUSSION: Adolescents exposed to ACEs experienced mutually reinforcing disadvantages: a worse mental health symptom burden, yet greater barriers to accessing needed medical and mental health care. ACEs must be reconceptualized as markers of structural-rather than individual-adversity and addressed through structural and policy interventions.

Indexed as

Adverse Childhood ExperiencesCOVID-19Health Services Needs and DemandAdolescentFemaleHealth Services AccessibilityHumansMaleMental DisordersPandemicsSARS-CoV-2United StatesAccess to careAdverse childhood experiences (ACEs)Coronavirus disease 2019 (COVID-19)Health care utilizationMental healthNeighborhood violenceParental incarceration

Identifiers

PMID40183723
PMCPMC12354138

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.