Evidence map›Paper›PMID 40183657›Full record

ArticleInfection & chemotherapy2025

Minocycline Susceptibility of Carbapenem-Resistant

Taeeun Kim, Eun Hee Jeon, Yoon-Kyoung Hong, Jiwon Jung, Min Jae Kim, Heungsup Sung, Mi-Na Kim, Sung-Han Kim, Sang-Ho Choi, Sang-Oh Lee and 2 more

Abstract read
In one paragraph

Article in Infection & chemotherapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Treating Extensively Drug-ResistantPathogens (Basel, Switzerland) · 2026
    Review
  3. Phenotypic and Genotypic Characterization of Carbapenem-ResistantInternational journal of microbiology · 2026
    Article
  4. Article
  5. Reply: Changing Genotypes andInfection & chemotherapy · 2025
    Article
  6. Changing Genotypes andInfection & chemotherapy · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Taeeun KimDivision of Infectious Diseases, Department of Medicine, Nowon Eulji University Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0002-2075-4497
Eun Hee JeonDepartment of Infectious Diseases, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Yoon-Kyoung HongDepartment of Infectious Diseases, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Jiwon JungDepartment of Infectious Diseases, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-4333-3270
Min Jae KimDepartment of Infectious Diseases, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-5489-8608
Heungsup SungDepartment of Laboratory Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-6062-4451
Mi-Na KimDepartment of Laboratory Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Sung-Han KimDepartment of Infectious Diseases, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-6596-8253
Sang-Ho ChoiDepartment of Infectious Diseases, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-4972-4531
Sang-Oh LeeDepartment of Infectious Diseases, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-1381-8787
Yang Soo KimDepartment of Infectious Diseases, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-6785-8824
Yong Pil ChongDepartment of Infectious Diseases, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. drchong@amc.seoul.kr.ORCID https://orcid.org/0000-0003-1672-3185

Funding

Korean Society for Antimicrobial Therapy
6 · The paper itself

Abstract

backgroundCarbapenem-resistant MATERIALS AND

methodsRepresentative CRAB blood isolates were collected from Asan Medical Center, Seoul. Minocycline susceptibility was assessed using the Clinical and Laboratory Standards Institute (CLSI) breakpoint (≤4 mg/L) and the proposed pharmacokinetics (PK)/pharmacodynamics (PD) breakpoint (≤1 mg/L). Tigecycline was used as a comparator, and its susceptibility breakpoint for

resultsOf the 160 CRAB blood isolates, 83.8% were susceptible to minocycline by the CLSI criteria, and 50.6% were PK-PD susceptible by the PK-PD criteria. The minocycline minimum inhibitory concentration (MIC)₅₀/MIC₉₀ was 1/8 mg/L.

conclusion

Indexed as

Acinetobacter baumanniiEfflux pumpMinocyclineResistancetetB

Identifiers

PMID40183657
PMCPMC11972901

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.