Evidence map›Paper›PMID 40183302›Full record

Trial reportCancer biomarkers : section A of Disease markers2025

The effect of low-intensity resistance exercise training on Serum tumor biomarkers and quality of life in women with breast cancer: A randomized controlled trial.

Deniz Kocamaz, Nahide Ayhan Fidancioğlu, Ramazan Cihad Yilmaz, Kübranur Ünal, Tülin Düger, Hüseyin Yüce Bircan, Yavuz Yakut

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Cancer biomarkers : section A of Disease markers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Deniz KocamazFaculty of Health Sciences, Department of Physiotherapy and Rehabilitation, Hasan Kalyoncu University, Gaziantep, Turkey.ORCID 0000-0002-0611-7686
Nahide Ayhan FidancioğluDepartment of Therapy and Rehabilitation, Ankara Yıldırım Beyazıt University, Health Services Vocatinal School, Ankara, Turkey.
Ramazan Cihad YilmazFaculty of Health Sciences, Department of Physiotherapy and Rehabilitation, Iğdir University, Iğdir, Turkey.
Kübranur ÜnalFaculty of Medicine, Department of Medical Biochemistry, Gazi University, Ankara, Turkey.ORCID 0000-0001-7940-4590
Tülin DügerDepartment of Physiotherapy and Rehabilitation, Hacettepe University Faculty of Physiotherapy and Rehabilitation, Ankara, Turkey.
Hüseyin Yüce BircanDepartment of First and Emergency Aid Program, Hasan Kalyoncu University, Vocatıonal School, Gaziantep, Turkey.
Yavuz YakutFaculty of Health Sciences, Department of Physiotherapy and Rehabilitation, Hasan Kalyoncu University, Gaziantep, Turkey.ORCID 0000-0001-9363-0869

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BackgroundAs the role of physical activity in breast cancer management gains increasing recognition, understanding the effects of aerobic exercise on patients' quality of life and biological markers has emerged as a critical area of research to inform clinical practices and improve patient outcomes.ObjectiveThis study aims to investigate the impact of low-intensity resistance exercise training on serum tumor biomarkers and quality of life in women with breast cancer, providing evidence for its potential role as an adjunct therapy in improving clinical outcomes and patient well-being.MethodsThis study was carried out on 70 women between the ages of 18 and 65, who were included in the study while receiving chemotherapy treatment. The subject was divided into low-intensity resistance exercise (Group I) and control (Group II). Demographic characteristics, quality of life, and serum tumor biomarkers were evaluated. Participants in group I underwent a 12-week exercise programme of low-intensity resistance exercises three times a week (three metabolic equivalents, approximately 30 min/session).ResultsThe quality of life has been found to be significantly higher in the low-intensity resistance exercise group (p < 0.05). The serum tumor biomarker levels of CEA, CA15-3, and CA19-9 decreased across all participants. However, the reduction in serum tumor biomarker levels was found to be more pronounced in Group 1 (p < 0.05).ConclusionsLow-intensity resistance exercise has demonstrated a positive effect on the quality of life in women with breast cancer. Within the framework of oncological rehabilitation, aerobic exercise regimens may be preferred due to their role in promoting improvements in serum tumor biomarker levels and contributing to enhanced quality of life.

Indexed as

Biomarkers, TumorBreast NeoplasmsQuality of LifeResistance TrainingAdolescentAdultAgedFemaleHumansMiddle AgedYoung AdultBiomarkers, TumorBreast cancerlow-intensity resistance exerciseoncological rehabilitationquality of lifeserum tumor biomarkers

Identifiers

PMID40183302
PMCPMC12288403

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.